Results 201 to 210 of about 107,498 (264)

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó   +84 more
wiley   +1 more source

Heart Failure in Older Adults: Real-World Outcomes and Patient Profiles by Admission Service and Sex. [PDF]

open access: yesJ Clin Med
Bonanad C   +10 more
europepmc   +1 more source

Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez   +295 more
wiley   +1 more source

Biliary Tract Carcinoma: Real-World Evidence in a Developing Country. [PDF]

open access: yesCureus
Lema M   +10 more
europepmc   +1 more source

Pharmacokinetics, effectiveness and safety of certolizumab pegol in children and adolescents with active juvenile idiopathic arthritis: 9+‐year results from a multicenter, open‐label study

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients 2–17 years with active pcJIA and inadequate response ...
Hermine I Brunner   +28 more
wiley   +1 more source

Editorial: New insights in veterinary cancer immunology, volume II. [PDF]

open access: yesFront Vet Sci
Fonseca-Alves CE   +2 more
europepmc   +1 more source

Patellar Tendon Repair With Gracilis Autograft Augmentation and Anchor Fixation

open access: yesArthroscopy Techniques, EarlyView.
Abstract Patellar tendon rupture is a severe injury that disrupts knee extensor continuity and requires prompt surgical management. Although primary repair remains the standard treatment, isolated suture repair may be insufficient in cases of poor tissue quality or high mechanical demand, making augmentation necessary.
Luis Henrique Longo   +6 more
wiley   +1 more source

Disease complexity, not surgical approach, predicts outcomes in xanthogranulomatous pyelonephritis. [PDF]

open access: yesInvestig Clin Urol
Lagos-Beitz HE   +7 more
europepmc   +1 more source

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