A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs [PDF]
, 2019 Accurate meiotic chromosome segregation critically depends on the formation of inter-homolog crossovers initiated by double-strand breaks (DSBs). Inaccuracies in this process can drive aneuploidy and developmental defects, but how meiotic cells are ...
Aguilera López, Andrés +7 more
core +1 more source
The C. elegans DSB-2 protein reveals a regulatory network that controls competence for meiotic DSB formation and promotes crossover assurance. [PDF]
, 2013 For most organisms, chromosome segregation during meiosis relies on deliberate induction of DNA double-strand breaks (DSBs) and repair of a subset of these DSBs as inter-homolog crossovers (COs).
Dernburg, Abby +6 more
core +2 more sources
The impact of body armor on physical performance of law enforcement personnel: A systematic review [PDF]
, 2017 Background The law enforcement officer profession requires performance of arduous occupational tasks while carrying an external load, consisting of, at minimum, a chest rig, a communication system, weaponry, handcuffs, personal protective equipment and a
Orr, Robin Marc +2 more
core +1 more source
Report on the 2013 Rapid Assessment Survey of Marine Species at New England Bays and Harbors [PDF]
, 2014 Introduced species (i.e., non-native species that have become established in a new location) have increasingly been recognized as a concern as they have become more prevalent in marine and terrestrial environments (Mooney and Cleland 2001; Simberloff et ...
Cao, Yuangyu +19 more
core +4 more sources
Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. [PDF]
, 2006 Immunophilin is the collective name given to the cyclophilin and FK506-binding protein (FKBP) families. As the name suggests, these include the major binding proteins of certain immunosuppressive drugs: cyclophilins for the cyclic peptide cyclosporin A ...
Adams +101 more
core +1 more source
Hydraulic fracturing in cells and tissues: fracking meets cell biology [PDF]
, 2017 The animal body is fundamentally made of water. A small fraction of this water is freely flowing in blood and lymph, but most of it is trapped in hydrogels such as the extracellular matrix (ECM), the cytoskeleton, and chromatin.
Arroyo Balaguer, Marino +1 more
core +4 more sources
Involvement of heparanase in the pathogenesis of acute kidney injury: Nephroprotective effect of PG545 [PDF]
, 2017 Despite the high prevalence of acute kidney injury (AKI) and its association with increased morbidity and mortality, therapeutic approaches for AKI are disappointing. This is largely attributed to poor understanding of the pathogenesis of AKI. Heparanase,
Abassi, Zaid +16 more
core +1 more source
Pediatric Liver Transplantation: Then and Now [PDF]
, 2020 This paper reviews the past 50 years of liver transplantation in children from the perspective of patient demographics, perioperative patient management, surgical techniques, immunosuppression and patient ...
Banh, DPT +4 more
core +1 more source
Arthritis Care &Research, Accepted Article.Objectives Australian evidence on lived and care experiences of chronic musculoskeletal shoulder pain (CMSP), irrespective of disorder classification or disease, is limited. However, such evidence is important for person‐centred care and informing local service pathways and care guidelines or standards.
Sonia Ranelli +8 more
wiley +1 more source
Metamodeling of Void Closure during Hot Flat Rolling
steel research international, EarlyView.This work aims to present a fast metamodel for void closure during hot flat rolling. The model takes into account every individual void of void distributions as found in industrial material and is capable of calculating the resulting void closure within only few seconds of computational time without loosing significant accuracy compared to expensive ...
Jannik Gerlach +2 more
wiley +1 more source