MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA [PDF]
, 2012 Topoisomerase II creates a double-strand break intermediate with topoisomerase covalently coupled to the DNA via a 5'-phosphotyrosyl bond. These intermediate complexes can become cytotoxic protein-DNA adducts and DSB repair at these lesions requires ...
Austin, Caroline +10 more
core +3 more sources
Annals of Applied Biology, Volume 188, Issue 1, Page 160-169, January 2026.Plant essential oils (EOs) represent a potentially effective, safe, and eco‐friendly alternative to synthetic pesticides that cause negative effects for human health and the environment. The present study evaluated in airtight glass chambers the toxicity of vapours produced by EOs obtained from sweet gale, balsam poplar, Labrador tea, jack pine, and ...
Antoine Roy‐Lemieux +4 more
wiley +1 more source
Force Steadiness During a Cognitively Challenging Motor Task Is Predicted by Executive Function in Older Adults [PDF]
, 2018 Motor performance and cognitive function both decline with aging. Older adults for example are usually less steady for a constant-force task than young adults when performing low-intensity contractions with limb muscles.
Hunter, Sandra K. +3 more
core +1 more source
Economic Determinants of Invasion and Discovery of Nonindigenous Insects [PDF]
Introductions of nonindigenous organisms into the United States have been linked to international trade. The individual contributions of imports, immigration, and international travel, however, are poorly understood because introduction dates are ...
Hlasny, Vladimir, Livingston, Michael J.
core +1 more source
Natural regeneration of broadleaved tree species in southern Sweden [PDF]
, 2001 The objective of the present thesis was to examine the effects of silvicultural treatments and seed dispersal from surrounding stands on the establishment of natural regeneration of broadleaved tree species in southern Sweden.
Karlsson, Matts
core
A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI [PDF]
, 2013 BACKGROUND: Acute kidney injury (AKI) is a frequent condition in hospitalised patients undergoing major surgery or the critically ill and is associated with increased mortality.
Delles, C. +6 more
core +3 more sources
Prevalence of chronic kidney disease and its associated risk factors: The first report from Iran using both microalbuminuria and urine sediment [PDF]
, 2012 Background: The incidence of major risk factors of chronic kidney disease (CKD) in the world is on the rise, and it is expected that this incidence and prevalence, particularly in developing countries, will continue to increase.
Alatab, S. +13 more
core
Molecular determinants of acute kidney injury [PDF]
, 2015 BACKGROUND: Acute kidney injury (AKI) is a condition that leads to a rapid deterioration of renal function associated with impairment to maintain electrolyte and acid balance, and, if left untreated, ultimately irreversible kidney damage and renal ...
Human, Christin, Husi, Holger
core +2 more sources
Inflammation and premature aging in advanced chronic kidney disease [PDF]
, 2017 Systemic inflammation in end-stage renal disease (ESRD) is an established risk factor for mortality and a catalyst for other complications which are related to a premature aging phenotype, including muscle wasting, vascular calcification and other forms ...
Casper G. Schalkwijk +9 more
core +1 more source
The role of marine reserves in achieving sustainable fisheries (One contribution of 15 to a Theme Issue 'Fisheries: a Future?') [PDF]
, 2005 Many fishery management tools currently in use have conservation value. They are designed to maintain stocks of commercially important species above target levels.
Alcala A. C. +15 more
core +2 more sources