Results 341 to 350 of about 162,227 (374)
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Journal of Agricultural and Food Chemistry, 2019
Carnitine, a dietary quaternary amine mainly from red meat, is metabolized to trimethylamine (TMA) by gut microbiota and subsequently oxidized to trimethylamine-N-oxide (TMAO) by host hepatic enzymes, flavin monooxygenases (FMOs).
Pei-Yu F. Chen +6 more
semanticscholar +1 more source
Carnitine, a dietary quaternary amine mainly from red meat, is metabolized to trimethylamine (TMA) by gut microbiota and subsequently oxidized to trimethylamine-N-oxide (TMAO) by host hepatic enzymes, flavin monooxygenases (FMOs).
Pei-Yu F. Chen +6 more
semanticscholar +1 more source
Current Opinion in Gastroenterology, 2012
Carnitine and its derivatives are natural substances involved in both carbohydrate and lipid metabolism. This review summarizes the recent progress in the field in relation to the molecular mechanisms.The pool of different carnitine derivatives is formed by acetyl-L-carnitine (ALC), propionyl-L-carnitine (PLC), and isovaleryl-carnitine.
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Carnitine and its derivatives are natural substances involved in both carbohydrate and lipid metabolism. This review summarizes the recent progress in the field in relation to the molecular mechanisms.The pool of different carnitine derivatives is formed by acetyl-L-carnitine (ALC), propionyl-L-carnitine (PLC), and isovaleryl-carnitine.
openaire +3 more sources
Carnitine Palmitoyltransferase Deficiencies
Molecular Genetics and Metabolism, 1999Carnitine palmitoyltransferase (CPT) deficiencies are common disorders of mitochondrial fatty acid oxidation. The CPT system is made up of two separate proteins located in the outer- (CPT1) and inner- (CPT2) mitochondrial membranes. While CPT2 is a ubiquitous protein, two tissue-specific CPT1 isoforms-the so-called "liver" (L) and "muscle" (M) CPT1s ...
J P, Bonnefont +6 more
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Drugs & Aging, 1998
Propionyl-L-carnitine stimulates energy production in ischaemic muscles by increasing citric acid cycle flux and stimulating pyruvate dehydrogenase activity. The free radical scavenging activity of the drug may also be beneficial. Propionyl-L-carnitine improves coagulative fibrinolytic homeostasis in vasal endothelium and positively affects blood ...
L R, Wiseman, R N, Brogden
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Propionyl-L-carnitine stimulates energy production in ischaemic muscles by increasing citric acid cycle flux and stimulating pyruvate dehydrogenase activity. The free radical scavenging activity of the drug may also be beneficial. Propionyl-L-carnitine improves coagulative fibrinolytic homeostasis in vasal endothelium and positively affects blood ...
L R, Wiseman, R N, Brogden
openaire +2 more sources
[Carnitine deficiency and carnitine therapy].
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1988The main function of carnitine is the transport of fatty acids across the inner mitochondrial membrane to the side of beta-oxidation. In healthy subjects no carnitine deficiency occurs. There are many inborn errors with carnitine deficiency as a primary genetic defect or secondary to other familial disorders of metabolism.
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Carnitine analogues and carnitine palmitoyltransferases
Biochemical Society Transactions, 1990M S, Murthy, R R, Ramsay, S V, Pande
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The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis.
European Journal of Biochemistry, 1997J. McGarry, N. Brown
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