Results 111 to 120 of about 21,879 (258)

Oxidative stress: new insights on the association of nonalcoholic fatty liver disease and atherosclerosis [PDF]

open access: yes, 2015
Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH), which may progress ...
Albanese, Fabiana   +7 more
core   +1 more source

Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes

open access: yesGlia, Volume 74, Issue 3, March 2026.
ALS models display increased LD accumulation. LD accumulation is linked to a neurotoxic phenotype in astrocytes. Lactate dehydrogenase inhibition reverts LD accumulation in ALS astrocytes. ABSTRACT Astrocytes are central to lipid metabolism in the central nervous system.
Daniel Esteve   +5 more
wiley   +1 more source

Preparació de 3-azidocumarines i derivats alquínics d’àcids grassos per reaccions “click”. [PDF]

open access: yes, 2015
Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2015, Tutor: Jordi Garcia GómezClick chemistry is evolving as a powerful tool in biological applications because it allows the sensitive and specific detection of ...
Torralvo Martín, Héctor
core  

Rhabdomyolysis Associated with Recent SARS-COV-2 Infection in a Patient with Carnitine Palmitoyltransferase II Deficiency [PDF]

open access: diamond, 2022
Irena Rambabova‐Bushljetik   +8 more
openalex   +1 more source

BiGraph‐DTA: Predicting drug–target interactions of hepatoprotective agents with graph convolutional networks

open access: yesQuantitative Biology, Volume 14, Issue 1, March 2026.
Abstract Predicting drug–target affinity (DTA) is critical for discovering and developing hepatoprotective agents that can prevent and treat liver diseases. In this study, we propose BiGraph‐DTA, a new predictive model for identifying DTA score prediction for hepatoprotective compounds by combining graph convolutional networks and bidirectional long ...
Arief Sartono   +4 more
wiley   +1 more source

A Human Model of Oligodendrocyte Development Shows MCL‐1 Influences Oligodendrocyte Morphogenesis

open access: yesGlia, Volume 74, Issue 2, February 2026.
A unified model of oligodendrocyte differentiation from human embryonic stem cells revealed that MCL‐1 is critical for regulating the expression of oligodendrocyte‐related genes and the morphogenesis of myelinating oligodendrocytes. ABSTRACT Oligodendrocytes are the myelinating cells of the central nervous system.
Melanie Gil   +2 more
wiley   +1 more source

Anti-Adipogenic Effects of Delphinidin-3-O-β-Glucoside in 3T3-L1 Preadipocytes and Primary White Adipocytes

open access: yesMolecules, 2019
Delphinidin-3-O-β-glucoside (D3G) is a health-promoting anthocyanin whose anti-obesity activity has not yet been thoroughly investigated. We examined the effects of D3G on adipogenesis and lipogenesis in 3T3-L1 adipocytes and primary white ...
Miey Park, Anshul Sharma, Hae-Jeung Lee
doaj   +1 more source

Sertraline‐Associated Riboflavin‐Responsive Lipid Storage Myopathy: Report of Two Case

open access: yesMuscle &Nerve, Volume 73, Issue 2, Page 309-312, February 2026.
Sertraline exposure can lead to an acquired riboflavin‐responsive multiple acyl‐CoA dehydrogenase deficiency (MADD). In patients with this acquired form of MADD, riboflavin supplementation can even lead to full clinical recovery and marked serological recovery before discontinuation of sertraline.
Aziz Shaibani, Alexis Taylor
wiley   +1 more source

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