Results 131 to 140 of about 21,879 (258)

CIDEC Restricts Liver Regeneration by Disturbing Lipid Droplet Triglyceride Turnover

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
This study identifies CIDEC, an lipid droplet (LD)‐fusion associated protein upregulated by CREBH during early regeneration, as a negative regulator of liver regeneration through its unexpected role in sequestering triglyceride (TG) within LDs. CIDEC depletion reduces LD size, mobilizes LD‐stored TG, enhances TG catabolism and free fatty acid (FFA ...
Feng Ouyang   +16 more
wiley   +1 more source

Hepatic Carnitine Palmitoyltransferase I Deficiency: Acylcarnitine Profiles in Blood Spots Are Highly Specific [PDF]

open access: bronze, 2001
Ralph Fingerhut   +10 more
openalex   +1 more source

Mechanistic Insights and Therapeutic Potential of Small Nucleolar RNA Host Genes in the Carcinogenesis of Hepatocellular Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) is one of the major factors endangering human health due to its poor prognosis, resulting from difficulties in early diagnosis and lack of effective treatment measures. Long non‐coding RNAs (lncRNAs), which are RNA molecules that do not translate into proteins, play essential roles in various tumor ...
Jiajia Luo   +2 more
wiley   +1 more source

Sulfur dioxide-free wine with polyphenols promotes lipid metabolism via the Nrf2 pathway and gut microbiota modulation

open access: yesFood Chemistry: X
Moderate wine consumption is often associated with preventing obesity, yet concerns arise due to the health risks linked to its constituent antioxidant, SO2. Recent focus has turned to polyphenols as a potential substitute for SO2.
Yi Ma   +7 more
doaj   +1 more source

Fabrication of Fructooligosaccharide‐Larimichthys crocea Peptide Copolymer by Wet‐Heating for Enhanced Calcium Delivery and Bone‐Lipid Metabolism Regulation

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
A food‐derived fructooligosaccharide‐Larimichthys crocea peptide (FOS‐LCP) copolymer was prepared by wet‐heating and exhibited high calcium‐binding capacity and enhanced intestinal calcium uptake compared with native peptides. In bone marrow mesenchymal stem cells from calcium‐deficient mice, FOS‐LCP was found to promote osteogenesis while suppressing ...
Chunlei Liu   +3 more
wiley   +1 more source

Partial Replacement of Maltodextrin With Galactose in Post‐Weaning Diets of Mice Alters Body Composition and Energy Metabolism in Early‐Life and Programs Hepatic Igf1 Expression in Later‐Life

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Galactose‐containing post‐weaning diets given for 3 weeks decreased body weight and changed energy metabolism compared to a maltodextrin‐enriched control diet in the early life of mice. After following 9 weeks of a high‐fat diet intervention, the mice fed in the early life the galactose‐containing diets had no obvious nutritional programming effects ...
Peixin Sun   +5 more
wiley   +1 more source

Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health

open access: yesJournal of Internal Medicine, Volume 299, Issue 1, Page 20-43, January 2026.
Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli   +12 more
wiley   +1 more source

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