Results 11 to 20 of about 21,999 (257)

Expression Of Carnitine Palmitoyltransferase I Isotypes In Gingival Tissues

International Dental Journal
Aim or purpose: Carnitine palmitoyltransferase I (CPT1), the rate-limiting enzyme of fatty acid oxidation, plays a crucial role in inflammation. However, the relation between CPT1 and periodontitis is obscure.
Yue Shen, Eryi Lu, Yuting Gu, Min Jin, Zhurong Cui, Tingting Lin, Shucheng Hu, Yuanjie Shi, Lu Lin, Weijun Yu   +9 more
doaj   +2 more sources

Altered carnitine-acylcarnitine profiles in levothyroxine-treated congenital hypothyroid patients with fatigue: An LC-MS/MS-based study from Bangladesh. [PDF]

PLoS ONE
Congenital hypothyroidism (CH), characterized by insufficient thyroid hormone production at birth, is frequently associated with fatigue, particularly in cases with delayed diagnosis. This study employed liquid chromatography-tandem mass spectrometry (LC-
Mst Noorjahan Begum, Suprovath Kumar Sarker, Md Tarikul Islam, Golam Sarower Bhuyan, Rumana Mahtarin, Mohammad Hridoy Patwary, Tasnia Kawsar Konika, Syeda Kashfi Qadri, Tasnuva Ahmed, Hurjahan Banu, Nusrat Sultana, Asifuzzaman Rahat, Kohinoor Jahan Shyamaly, Taufiqur Rahman Bhuiyan, Mizanul Hasan, Mohammad A Hasanat, Abu A Sajib, Abul B M M K Islam, Kaiissar Mannoor, Sharif Akhteruzzaman, Firdausi Qadri   +20 more
doaj   +2 more sources

Optimal Dietary α-Starch Requirement and Its Effects on Growth and Metabolic Regulation in Chinese Hook Snout Carp (Opsariichthys bidens) [PDF]

Biology
This study investigated the effects of dietary carbohydrate levels on growth performance, body composition, and hepatic expression of metabolic genes in Chinese hook snout carp (Opsariichthys bidens). Fish were fed five isonitrogenous diets with graded α-
Wenjing Cai, Xiaonian Luo, Jiao Li, Youjian Duan, Yong Wei, Yuxin Xing, Zongyun Hu, Chunyue Zhu   +7 more
doaj   +2 more sources

Determination of Metabolomics Profiling in BPA-Induced Impaired Metabolism

Pharmaceutics, 2022
Exposure to bisphenol A (BPA) is unavoidable and it has far-reaching negative effects on living systems. This study aimed to explore the toxic effects of BPA in an experimental animal model through a metabolomics approach that is useful in measuring ...
Maria Alvi, Kanwal Rehman, Muhammad Sajid Hamid Akash, Azka Yaqoob, Syed Muhammad Shoaib   +4 more
doaj   +1 more source

Longitudinal Metabolomic Profiling of Amino Acids and Lipids across Healthy Pregnancy [PDF]

, 2015
Pregnancy is characterized by a complexity of metabolic processes that may impact fetal development and ultimately, infant health outcomes. However, our understanding of whole body maternal and fetal metabolism during this critical life stage remains ...
Ashton, Nick, Buss, Claudia, Entringer, Sonja, Hellmuth, Christian, Koletzko, Berthold, Lindsay, Karen L, Uhl, Olaf, Wadhwa, Pathik D   +7 more
core   +16 more sources

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Dietary copper supplementation modulates performance and lipid metabolism in meat goat kids

Journal of Integrative Agriculture, 2023
Forty-eight male Lezhi black goat kids with similar body weight ((12.09±1.70) kg) and age ((60±5) d) were used to determine the effect of dietary copper (Cu), in the form of reagent grade Cu sulfate (CuSO4·5H2O), on performance, serum lipid profile, and ...
Yan-mei ZHANG, De AO, Kai-wen LEI, XI Lin, Jerry W. SPEARS, Hai-tao SHI, Yan-ling HUANG, Fa-long YANG   +7 more
doaj   +1 more source

Glial β-Oxidation regulates drosophila energy metabolism [PDF]

, 2015
The brain's impotence to utilize long-chain fatty acids as fuel, one of the dogmas in neuroscience, is surprising, since the nervous system is the tissue most energy consuming and most vulnerable to a lack of energy.
Bastianen, Jarl, Dotti, Carlos G., Gärtner, Annette, Laranjeira, Antonio, Shulz, Joachim G., Van Huffel, Leen, Van Veldhoven, Paul P., Vilain, Sven   +7 more
core   +5 more sources

Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts

Journal of Lipid Research, 1998
The relationship between peroxisomal and mitochondrial oxidation of the methyl branched fatty acids, phytanic acid and pristanic acid, was studied in normal and mutant human skin fibroblasts with established enzyme deficiencies.
Nanda M. Verhoeven, Diane S. Roe, Robert M. Kok, Ronald J.A. Wanders, Cornelis Jakobs, Charles R. Roe   +5 more
doaj   +1 more source