Results 221 to 230 of about 21,999 (257)

Carnitine. [PDF]

open access: yesAdv Nutr
Lin X, Adams SH, Vockley J, Odle J.
europepmc   +1 more source

Predictive Role of Metabolic Profiling in Rivaroxaban Efficacy for Thrombus Lysis in Atrial Fibrillation. [PDF]

open access: yesInt J Mol Sci
Michorowska S   +4 more
europepmc   +1 more source

Inhibition of systemic mammalian metabolism by carnitine mimics from the gut microbiota

open access: yes
Thümmler K   +20 more
europepmc   +1 more source
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Deficiency of Carnitine Palmitoyltransferase I

Journal of Child Neurology, 1989
Defective activity of carnitine palmitoyltransferase I was demonstrated in fibroblasts derived from a patient with hypoketotic hypoglycemia. The level of activity observed was approximately 10% of the control mean. Oxidation of palmitate by intact fibroblasts was reduced to 5% of control values. The patient presented at age 14 months with seizures and
J P, Bonnefont   +8 more
openaire   +2 more sources

Hyperlipidaemia due to carnitine palmitoyltransferase I deficiency

Journal of Inherited Metabolic Disease, 2006
SummaryWe report a patient with carnitine palmitoyltransferase I (CPT I) deficiency, who presented with acute encephalopathy at 6 months of age. This was precipitated by an episode of gastroenteritis. No hypoglycaemia was documented, but there was hepatomegaly; blood tests revealed raised transaminases, a coagulopathy and severe hypertriglyceridaemia ...
H, Worthington   +3 more
openaire   +2 more sources

Carnitine palmitoyltransferase I

European Journal of Biochemistry, 1983
Palmitate oxidation by liver mitochondria from rats treated with d‐galactosamine (GalN) was markedly inhibited, 3 h after administration. The mitochondrial defect responsible for this inhibition was shown to be an inhibition of the activity of palmitoylcarnitine transferase I (EC 2.3.1.21). Apparent Km of the enzyme remained unchanged whereas apparent
O, Sire   +4 more
openaire   +2 more sources

Features of carnitine palmitoyltransferase type I deficiency

Journal of Inherited Metabolic Disease, 2001
AbstractCarnitine palmitoyltransferase type I (CPT I) is unique among long‐chain fatty acid oxidation enzymes in that there are two tissue‐specific isoforms, ‘hepatic’ and ‘muscle’, which are encoded by two separate genes. The ‘hepatic’ isoform is expressed in liver, kidney and fibroblasts and at low levels in the heart, while the other isoform occurs ...
S E, Olpin   +12 more
openaire   +2 more sources

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