Results 31 to 40 of about 21,999 (257)

Does skeletal muscle carnitine availability influence fuel selection during exercise? [PDF]

, 2018
This is the author accepted manuscript. The final version is available from Cambridge University Press via the DOI in this record.Fat and carbohydrate are the major fuel sources utilised for oxidative, mitochondrial ATP resynthesis during human skeletal ...
Stephens, FB
core   +1 more source

Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal [PDF]

Biochemical Journal, 2004
CPT I (carnitine palmitoyltransferase I) catalyses the conversion of palmitoyl-CoA into palmitoylcarnitine in the presence of l-carnitine, facilitating the entry of fatty acids into mitochondria. We propose a 3-D (three-dimensional) structural model for L-CPT I (liver CPT I), based on the similarity of this enzyme to the recently crystallized mouse ...
Montserrat, Morillas, Eduardo, López-Viñas, Alfonso, Valencia, Dolors, Serra, Paulino, Gómez-Puertas, Fausto G, Hegardt, Guillermina, Asins   +6 more
openaire   +2 more sources

Comparison of Properties of Carnitine Palmitoyltransferase I with Those of Carnitine Palmitoyltransferase II, and Preparation of Antibodies to Carnitine Palmitoyltransferases

Journal of Biological Chemistry, 1973
Abstract Carnitine palmitoyltransferase II has been partially purified. Its properties have been found to differ from those of carnitine palmitoyltransferase I (EC 2.3.1.23) in the following ways. (a) Carnitine palmitoyltransferase II catalyzes the reaction only in the direction towards long chain fatty acyl-CoA formation.
B, Kopec, I B, Fritz
openaire   +2 more sources

Branched-Chain Fatty Acids as Mediators of the Activation of Hepatic Peroxisome Proliferator-Activated Receptor Alpha by a Fungal Lipid Extract

Biomolecules, 2020
The study aimed to test the hypothesis that monomethyl branched-chain fatty acids (BCFAs) and a lipid extract of Conidiobolus heterosporus (CHLE), rich in monomethyl BCFAs, are able to activate the nuclear transcription factor peroxisome proliferator ...
Garima Maheshwari, Robert Ringseis, Gaiping Wen, Denise K. Gessner, Johanna Rost, Marco A. Fraatz, Holger Zorn, Klaus Eder   +7 more
doaj   +1 more source

Influence of aerobic physical training in the motochondrial transport of long chain fatty acids in the skeletal muscle: role of the carnitine palmitoil transferase [PDF]

, 2008
O ácido graxo (AG) é uma importante fonte de energia para o músculo esquelético. Durante o exercício sua mobilização é aumentada para suprir as necessidades da musculatura ativa.
CARNEVALI JR., Luiz Carlos, GONÇALVES, Daniela Caetano, LIMA, Waldecir Paula, LIRA, Fábio Santos, SEELAENDER, Marília Cerqueira Leite, TAVARES, Fábio Luis, YAMASHITA, Alex Shimura   +6 more
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Mechanisms of liver steatosis in rats with systemic carnitine deficiency due to treatment with trimethylhydraziniumpropionate

Journal of Lipid Research, 2003
Rats with systemic carnitine deficiency induced by treatment with trimethylhydraziniumpropionate (THP) develop liver steatosis. This study aims to investigate the mechanisms leading to steatosis in THP-induced carnitine deficiency. Rats were treated with
Markus Spaniol, Priska Kaufmann, Konstantin Beier, Jenny Wüthrich, Michael Török, Hubert Scharnagl, Winfried März, Stephan Krähenbühl   +7 more
doaj   +1 more source

Multi-Omics Analyses Detail Metabolic Reprogramming in Lipids, Carnitines, and Use of Glycolytic Intermediates between Prostate Small Cell Neuroendocrine Carcinoma and Prostate Adenocarcinoma. [PDF]

, 2019
As the most common cancer in men, prostate cancer is molecularly heterogeneous. Contributing to this heterogeneity are the poorly understood metabolic adaptations of the two main types of prostate cancer, i.e., adenocarcinoma and small cell ...
Alumkal, Joshi J, Fan, Sili, Fiehn, Oliver, Gao, Bei, Lue, Hui-Wen, Podolak, Jennifer, Serawat, Archana, Thomas, George V, Zhang, Ying   +8 more
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Low Expression of Sirtuin 1 in the Dairy Cows with Mild Fatty Liver Alters Hepatic Lipid Metabolism

Animals, 2020
Dairy cows usually experience negative energy balance coupled with an increased incidence of fatty liver during the periparturient period. The purpose of this study was to investigate the effect of hepatic steatosis on the expression of the sirtuin 1 ...
Yu Li, Suping Zou, Hongyan Ding, Ning Hao, Yingying Huang, Jishun Tang, Jianbo Cheng, Shibin Feng, Jinchun Li, Xichun Wang, Jinjie Wu   +10 more
doaj   +1 more source

Reduction of brain mitochondrial β-oxidation impairs complex I and V in chronic alcohol intake: the underlying mechanism for neurodegeneration. [PDF]

PLoS ONE, 2013
Neuropathy and neurocognitive deficits are common among chronic alcohol users, which are believed to be associated with mitochondrial dysfunction in the brain. The specific type of brain mitochondrial respiratory chain complexes (mRCC) that are adversely
James Haorah, Travis J Rump, Huangui Xiong   +2 more
doaj   +1 more source

Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue [PDF]

, 2007
In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis).
Bianco, Antonio C., Christoffolete, Marcelo A., D'Eon, Tara M., Greenberg, Andrew S., Imachi, Hitomi, Miyoshi, Hideaki, Obin, Martin S., Perfield, James W., II, Ribeiro, Miriam O., Rogers, Nicole H., Souza, Sandra C., Stancheva, Zlatina S., Strissel, Katherine J.   +12 more
core   +1 more source