Results 41 to 50 of about 21,999 (257)
Pharmacogenomics and Personalized Medicine, 2023 Xiaoxia Wang, Haining Fang Department of Pediatrics, Maternal and Child Health Hospital of Hubei Province, Wuhan, 430070, People’s Republic of ChinaCorrespondence: Haining Fang, Department of Pediatrics, Maternal and Child Health Hospital of Hubei ...
Wang X, Fang H
doaj
Mitochondrial fatty acid oxidation in obesity [PDF]
, 2014 Significance: Current lifestyles with high-energy diets and little exercise are triggering an alarming growth in obesity. Excess of adiposity is leading to severe increases in associated pathologies, such as insulin resistance, type 2 diabetes ...
Herrero Rodríguez, Laura +4 more
core +2 more sources
Complementation Analysis of Carnitine Palmitoyltransferase I and II Defects [PDF]
Pediatric Research, 1996 Carnitine palmitoyltransferase (CPT) consists of two activities located in the outer (CPT I) and the inner (CPT II) mitochondrial membranes. CPT II deficiency in the adult as well as in the infantile form of the disease has been shown to result from mutations in the CPT II cDNA. Nothing is known regarding the genetic defect in CPT I deficiency.
A, Slama +5 more
openaire +2 more sources
Drug-Induced Inhibition of Mitochondrial Fatty Acid Oxidation and Steatosis [PDF]
, 2013 Mitochondrial Dysfunction and Diseases (H Jaeschke, Section Editor)International audienceDrug-induced inhibition of mitochondrial fatty acid β-oxidation (mtFAO) is a key mechanism whereby drugs can induce steatosis.
Begriche, Karima +5 more
core +3 more sources
Global Medical & Health Communication, 2018 Food deprivation is one of the extreme conditions that mammals have to survive. The majority of the tissues, excluding the brain and red blood cells, depend on the fatty acids (FA) utilization to produce energy.
Mirasari Putri +3 more
doaj +1 more source
Do the Effects of Resveratrol on Thermogenic and Oxidative Capacities in IBAT and Skeletal Muscle Depend on Feeding Conditions? [PDF]
, 2018 The aim of this study was to compare the effects of mild energy restriction and resveratrol on thermogenic and oxidative capacity in interscapular brown adipose tissue (IBAT) and in skeletal muscle.
Aguirre López, Leixuri +5 more
core +3 more sources
FishesIn order to study the effects of soybean isoflavones on the growth performance and lipid metabolism of juvenile Chinese mitten crabs, six experimental diets were formulated by gradient supplementation with 0%, 0.004% and 0.008% soybean isoflavones at ...
Mengyu Shi +8 more
doaj +1 more source
Pharmaceuticals, 2022 Accumulating evidence has highlighted that sirtuin-6 (SIRT6) plays an important role in hepatic gluconeogenesis and lipogenesis. We aim to investigate the underlying mechanisms and pharmacological interventions of SIRT6 on hepatic steatosis treatment ...
Danli Kong +13 more
doaj +1 more source
Cells, 2020 Obesity develops due to an energy imbalance and manifests as the storage of excess triglyceride (TG) in white adipose tissue (WAT). Recent studies have determined that edible natural materials can reduce lipid accumulation and promote browning in WAT. We
Heegu Jin +5 more
doaj +1 more source
Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism
Advanced Science, EarlyView.Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards +8 more
wiley +1 more source