Results 61 to 70 of about 21,879 (258)

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

Direct Expression of CPT1a Enables a High Throughput Platform for the Discovery of CPT1a Modulators

Applied Biosciences
Carnitine palmitoyltransferase 1 (CPT1), which catalyzes the rate-limiting step of fatty acid oxidation, has been implicated in therapeutic approaches to several human diseases characterized by aberrant lipid metabolism.
Jason Chen, Tuyen Tran, Anthony Wong, Luofei Wang, Pranavi Annaluru, Vibha Sreekanth, Samika Murthy, Laasya Munjeti, Tanya Park, Utkarsh Bhat, Glynnis Leong, Yumeng Li, Simeng Chen, Natalie Kong, Rushika Raval, Yining Xie, Shreya Somani, Aditi Manohar Bhambhani, Zoey Zhu, Landen Chu, Kimai Dosch, Edward Njoo, Zhan Chen   +22 more
doaj   +1 more source

Immunoquantitative Analysis of Human Carnitine Palmitoyltransferase I and II Defects [PDF]

Pediatric Research, 1990
Carnitine palmitoyltransferase deficiency realizes two distinct clinical forms. We previously showed and confirmed in the present work that CPTII (identified as the carnitine palmitoyltransferase activity assayable in detergent conditions) is decreased in the muscular form whereas it is unaffected and CPTI is decreased in the hepatic form. The antibody
F, Demaugre, J P, Bonnefont, C, Cepanec, J, Scholte, J M, Saudubray, J P, Leroux   +5 more
openaire   +2 more sources

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana, Guma, Monica, Murillo-Saich, Jessica D   +2 more
core   +2 more sources

Overview of Encapsulated Lysine and Methionine and Their Impacts on Transition Cow Performance and Health

Animal Research and One Health, EarlyView.
The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem, Samy A. Elsaadawy, Zhaohai Wu, Lu Ma, Todd R. Callaway, Dengpan Bu   +5 more
wiley   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, EarlyView.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source

Estratègies de modulació de l'oxidació d'àcids grassos com a tractament per combatre l'obesitat [PDF]

, 2015
L'estil de vida actual, amb dietes d'alt contingut calòric i falta d'exercici físic, fa que la incidència d'obesitat s'incrementi notablement.
Calderón-Domínguez, María, Herrero Rodríguez, Laura, Mir, Joan Francesc, Serra, Dolors, Weber Blattes, Minéia   +4 more
core  

Recurrent rhabdomyolysis caused by carnitine palmitoyltransferase II deficiency, common but under-recognised: Lessons to be learnt [PDF]

, 2018
We discuss two adult siblings who presented with symptoms of myalgia and rhabdomyolysis following exercise with myoglobinuria; genetic testing confirmed carnitine palmitoyltransferase II deficiency and resulted in institution of appropriate crisis ...
Balasubramanian, M., Gillett, G.T., Hill, M., Jenkins, T.M., Kirk, R.J., Nesbitt, I.M., Olpin, S.E.   +6 more
core   +2 more sources

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

Effets de l’acide trans-10, cis-12 linoléique sur le métabolisme des lipides dans le foie chez la souris C57BL/6

Oléagineux, Corps gras, Lipides, 2005
A 4-week diet containing 1% of the conjugated trans-10,cis-12 linoleic acid (CLA2) induces, in C57BL/6 mice, a lipodystrophy, a liver steatosis and a reduction of plasma triglycerides.
Degrace Pascal, Demizieux Laurent, Mohamed Ismaël, Gresti Joseph, Chardigny Jean-Michel, Sébédio Jean-Louis, Clouet Pierre   +6 more
doaj   +1 more source