Results 281 to 290 of about 242,261 (346)

Correlation between Morphological and Hemodynamic Parameters of Carotid Arteries and Cerebral Vasomotor Reactivity. [PDF]

open access: yesBrain Sci
Stoisavljevic S   +5 more
europepmc   +1 more source

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

open access: yesLipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao   +5 more
wiley   +1 more source

A paraoxonase gene polymorphism, PON 1 (55), as an independent risk factor for increased carotid intima-media tickness in middle-aged women. [PDF]

open access: yes, 2003
DE MICHELE M   +10 more
core  

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

open access: yesMed Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang   +13 more
wiley   +1 more source

Jointly Learned 3D Non‐Cartesian Sampling With Wave Encoding and Reconstruction for Neurovascular Phase Contrast MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop accelerated 3D phase contrast (PC) MRI using jointly learned wave encoding and reconstruction. Methods Pseudo‐fully sampled neurovascular 4D flow data (N = 40) and a simulation framework were used to learn phase encoding locations, wave readout parameters, and model‐based reconstruction network (MoDL) for a rapid 3D PC scan (
Chenwei Tang   +7 more
wiley   +1 more source

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