Results 91 to 100 of about 447,928 (350)

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

open access: yesAdvanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang   +15 more
wiley   +1 more source

Two Cases Treated by Different Strategies for Common Carotid Artery Dissection with Thrombosis Due to a Type A Aortic Dissection

open access: yesBrazilian Journal of Cardiovascular Surgery
Total arch replacement and stent trunk were performed for two patients. One of these underwent a total bilateral carotid artery replacement in anatomical position while the other underwent partial carotid artery dissection. The first patient demonstrated
Wei Ren   +4 more
doaj   +1 more source

Incidence of carotid artery stenosis in acute ischemic stroke at BMC Hospital Quetta [PDF]

open access: yesRomanian Journal of Neurology
Background and objectives. This study aimed to explore the prevalence, severity, and distribution of carotid artery stenosis among patients experiencing ischemic strokes. Materials and methods.
Muhammad Essa   +10 more
doaj   +1 more source

A comparison between local wave speed in the carotid and femoral arteries in healthy humans: application of a new method [PDF]

open access: yes, 2010
The wave speed (c) and the arrival time of reflected wave (Trw) in the common left carotid artery and common left femoral artery have been evaluated in 70 healthy subjects, aged 35-55 years with a non-invasive method.
Borlotti, Alessandra   +4 more
core   +2 more sources

Electrophysiological Studies of the Smooth Muscle Cell Membrane of the Rabbit Common Carotid Artery

open access: yesThe Journal of General Physiology, 1971
The electrical responses of the smooth muscle cells of the rabbit common carotid artery to extracellular stimulation were studied in isotonic and hypertonic solution (1.7 times normal tonicity) with microelectrodes.
F. Mekata
semanticscholar   +1 more source

Iron Overload Mediates the Differential Cell Fate of Astrocytes from Neurons and Its Regulatory Mechanisms in Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo   +17 more
wiley   +1 more source

Low prevalence of significant carotid artery disease in Iranian patients undergoing elective coronary artery bypass

open access: yesCardiovascular Ultrasound, 2007
Background Coronary artery bypass grafting ranks as one of the most frequent operations worldwide. The presence of carotid artery stenosis may increase the stroke rate in the perioperative period.
Karimi Fatemeh   +4 more
doaj   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

open access: yesAdvanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini   +4 more
wiley   +1 more source

Volumetric analysis of carotid plaque components and cerebral microbleeds: a correlative study [PDF]

open access: yes, 2017
PURPOSE: The purpose of this work was to explore the association between carotid plaque volume (total and the subcomponents) and cerebral microbleeds (CMBs).
Anzidei, Michele   +8 more
core   +1 more source

Manual and automated media and intima thickness measurements of the common carotid artery

open access: yesIEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2009
The intima-media thickness (IMT) of the common carotid artery (CCA) is widely used as an early indicator of the development of cardiovascular disease (CVD).
C. Loizou   +3 more
semanticscholar   +1 more source

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