Results 91 to 100 of about 6,207,455 (303)

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

Advanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu, Wen Zhang, Lunxin Liu, Lan Gui, Yumei Qin, Xiaohui Yang, Longjian Zhang, Chaohua Wang, Jinpeng Hu, Gaoyang Guo, Qing Jiang, Jin Wang, Li Yang, Bo Zhang, Yunbing Wang   +14 more
wiley   +1 more source

The superior thyroid artery arising from the common carotid artery at the level of the lamina of thyroid cartilage; CCA = Common carotid artery, ECA = External carotid artery, ICA = Internal carotid artery, STA = Superior thyroid artery, EBSLN = External branch of the superior laryngeal nerve.

, 2018
The superior thyroid artery arising from the common carotid artery at the level of the lamina of thyroid cartilage; CCA = Common carotid artery, ECA = External carotid artery, ICA = Internal carotid artery, STA = Superior thyroid artery, EBSLN = External
Meselech Ambaw Dessie (5204114)
core   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Two Cases Treated by Different Strategies for Common Carotid Artery Dissection with Thrombosis Due to a Type A Aortic Dissection

Brazilian Journal of Cardiovascular Surgery
Total arch replacement and stent trunk were performed for two patients. One of these underwent a total bilateral carotid artery replacement in anatomical position while the other underwent partial carotid artery dissection. The first patient demonstrated
Wei Ren, Feng Shi, Zhiwei Wang, Jiahui Wang, Jinxing Chang   +4 more
doaj   +1 more source

Letter to the Editor Fracture of a carotid stent and restenosis of common carotid artery

Archives of Medical Science, 2013
In recent years we have observed dynamic growth in the amount of carotid stenting (CAS) as an alternative to surgical endarterectomy (CEA) [1]. We present a case of stent fracture of a balloon-expanding stent in a patient who underwent stenting for stenoses of the common and internal left carotid arteries.
Wróbel, Wojciech, Lesiak, Maciej, Sinkiewicz, Anna   +2 more
openaire   +2 more sources

The superior thyroid artery arising from common carotid artery bifurcation at the level of the lamina of thyroid cartilage; CCA = Common carotid artery, ECA = External carotid artery, ICA = Internal carotid artery, STA = Superior thyroid artery, STV = Superior thyroid vein, EBSLN = External branch of the superior laryngeal nerve.

, 2018
The superior thyroid artery arising from common carotid artery bifurcation at the level of the lamina of thyroid cartilage; CCA = Common carotid artery, ECA = External carotid artery, ICA = Internal carotid artery, STA = Superior thyroid artery, STV ...
Meselech Ambaw Dessie (5204114)
core   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Incidence of carotid artery stenosis in acute ischemic stroke at BMC Hospital Quetta [PDF]

Romanian Journal of Neurology
Background and objectives. This study aimed to explore the prevalence, severity, and distribution of carotid artery stenosis among patients experiencing ischemic strokes. Materials and methods.
Muhammad Essa, Amanullah Kakar, Gul Andam, Noor Ahmed Khoso, Muhammad Saleem, Noman ul Haq, Anjum Farooq, Wazir Akber, Ihsan ul Haq, Paras Laraib, Shafqat Shahzad   +10 more
doaj   +1 more source

Salvianolic Acid a Disrupts the HSP90α‐AKT‐PERK Ternary Complex to Alleviate Atherosclerosis by Activating Endoplasmic Reticulum Stress of Senescent Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Salvianolic acid A (SAA) selectively induces senescent vascular smooth muscle cell apoptosis, alleviating atherosclerosis. Mechanistically, SAA targets heat shock protein 90 alpha (HSP90α) to disrupt the protein inase B (AKT)‐PRKR‐Like Endoplasmic Reticulum Kinase (PERK) scaffold, driving ubiquitin‐proteasome‐dependent AKT degradation.
Xiuya Guan, Mengkai Lu, Xinhai Cui, Dawei Zhang, Lei Zhang, Lin Lin, Yuan Li, Yuanlong Hu, Chao Li   +8 more
wiley   +1 more source