Results 121 to 130 of about 5,236,990 (302)

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Unilateral common carotid artery agenesis: Case report of a rare incidental finding

Radiology Case Reports
This case report follows a 60-year-old female with a history of hypertension, diabetes, and Factor V Leiden mutation with multiple prior deep vein thromboses (DVT) in the lower extremities who presented with right eye vision loss.
Aparna Medarametla, BS, Abel Tsehay Abebe, MD, Mohamed Tantawi, MD, Alaha Al Taweel, MD   +3 more
doaj   +1 more source

THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A

Advanced Science, EarlyView.
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu, Hongfei Liu, Yiqi Wan, Andong Wu, Jiayu Qiu, Xueting Gong, Ya Zhao, Yuanyuan Li, Bingbing Zhou, Yangyi Zheng, Fang Wu, Yuanzheng Zhu, Weixin Lv, Xueer Li, Qiang Yuan, Xiao‐Li Tian   +15 more
wiley   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source

Created Ex Nihilo: A Near‐Infrared Afterglow Luminescent Framework of Imidazole Derivatives for Bioimaging

Angewandte Chemie, EarlyView.
A series of Ir(III) complexes (Ir‐1‐Ir‐4) based on imidazole derivatives provide a new afterglow luminescence mechanism. The work expands the range of afterglow luminescence frameworks to overcome: (i) a lack of new afterglow scaffolds; (ii) the dependence on initial external light activation; and (iii) aggregation‐caused quenching.
Zihan Wu, Liping Zhang, Ziwei Wang, Yachao Wang, Gelin Xu, Feng Chi, Dongxia Zhu, Martin R. Bryce, Ben Zhong Tang, Lijie Ren   +9 more
wiley   +2 more sources

On the features of carotid artery bifurcation geometry in normal state and in stenosis

Сибирский научный медицинский журнал
Diseases of the brachiocephalic arteries are among the most common pathologies of the human cardiovascular system. Stenosis of the carotid bifurcation is treated surgically by performing either carotid endarterectomy or carotid artery stenting ...
D. S. Chutkov, D. V. Tikhvinskii, A. V. Dubovoy, A. V. Gogolev, D. V. Parshin   +4 more
doaj   +1 more source

Smart Flexible Tactile Sensors: Recent Progress in Device Designs, Intelligent Algorithms, and Multidisciplinary Applications

Advanced Intelligent Discovery, EarlyView.
Flexible tactile sensors have considerable potential for broad application in healthcare monitoring, human–machine interfaces, and bioinspired robotics. This review explores recent progress in device design, performance optimization, and intelligent applications. It highlights how AI algorithms enhance environmental adaptability and perception accuracy
Siyuan Wang, Ming Dong, Rongrong Bao, Caofeng Pan   +3 more
wiley   +1 more source

Effects of smoking on carotid artery structures and haemodynamics: role of the radiographer in ultrasound assessment [PDF]

, 2018
The goal of this research was to assess the effect of tobacco on structural and haemodynamic parameters in carotid arteries. 103 subjects (51 smokers and 52 non-smokers) were evaluated by a trained radiographer using ultrasound equipment. The smokers
Abrantes, António, Simão, Diogo, Pinheiro, João, Rodrigues, Sónia, Almeida, Rui, Ribeiro, Luís   +5 more
core   +1 more source

Segmented Therapeutic Delivery via Acoustic Microbubble Relay

Advanced Intelligent Systems, EarlyView.
An acoustically driven, modular segmented delivery system is presented to overcome mechanical limitations of conventional microcatheters. Oscillating microbubbles generate directional streaming that enables continuous, targeted transport across open, angled segments.
Lei Wang, Yiyang Tang, Yiqiang Wu, Xin Zhang, Tianshi Lyu, Zhen Hua, Tian‐Yun Huang   +6 more
wiley   +1 more source

A rare association of curving and looping of internal carotid artery and variation in the branching pattern of external carotid artery - a case report [PDF]

International Journal of Biological and Medical Research, 2011
: During the routine dissection of neck region in an approx 50 year old male cadaver in the department of Anatomy at Maharajah’s Institute Of Medical Sciences, Vizianagaram, a rare unilateral variation in the branching pattern of common carotid artery ...
Sunitha Vinnakota, Bhimaidevi Nandagiri, Jayasree Neelee   +1 more
doaj