Integrated scRNA‐seq and spatial multiomics provide single‐cell and spatial insights into the neuroprotective effects of NGR1, a clinically validated bioactive compound from Panax notoginseng. NGR1 was associated with a shift in microglial transcriptional states away from ischemia‐associated pro‐inflammatory Adam8hi microglia and toward the protective ...
Qikun Zhao +10 more
wiley +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Computational Fluid Dynamics Analysis of Contrast Agent Distribution in Acute Large Artery Occlusive Stroke: A Preliminary Proof-of-Concept Study. [PDF]
Wu J, Xu G, Gan Q, Shi R, Cao L, Fu P.
europepmc +1 more source
Metrnl: A Novel Therapeutic Target in Atherosclerosis
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley +1 more source
Sustained Tocilizumab and Adjunctive HydroBox Therapy in Refractory Takayasu Arteritis: An 11-year Case Report. [PDF]
Liao CY +6 more
europepmc +1 more source
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi +15 more
wiley +1 more source
Mapping the lingual artery: a scoping review and proposed imaging-informed risk classification for surgical and radiological practice. [PDF]
Landfald IC +9 more
europepmc +1 more source
Acute Effects of Smoking and Vaping on Markers of Vascular Function via Quantitative MRI
ABSTRACT Background E‐cigarettes contribute to endothelial dysfunction, a known cause of systemic atherosclerotic disease that cannot be adequately characterized by a single physiological parameter measured at a single vascular bed. Purpose/Hypothesis Quantify and compare acute effects of smoking or vaping with tobacco cigarettes (t‐cigs), nicotinized ...
Marianne Nabbout +9 more
wiley +1 more source
Compressed Branching Geometry in a Bovine-Type Aortic Arch: A Morphometric Cadaveric Case Report and Systematic Review of the Literature. [PDF]
Naoun AA, Figueroa Monsanto HL, Veras W.
europepmc +1 more source
Clinical Images: Rapidly progressive granulocyte colony-stimulating factor-associated arteritis: initial normal imaging as a diagnostic pitfall. [PDF]
Kayabe Kuroda C +7 more
europepmc +1 more source

