Results 91 to 100 of about 241,952 (314)

Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives

open access: yesAdvanced Science, EarlyView.
Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley   +1 more source

Ultra‐Sensitive and Linear Flexible Pressure Sensors with Tri‐Scale Graded Microstructures for Advanced Health Monitoring and Robotic Perception

open access: yesAdvanced Science, EarlyView.
A flexible piezoresistive sensor with a 3D tri‐scale graded microstructure is proposed, overcoming the trade‐off between sensitivity and linearity. The device achieves ultra‐high sensitivity (138.6 kPa−1), a broad linear range (400 kPa, R2 = 0.99), and exceptional stability (24 000 repeated loading cycles), enabling precise detection of physiological ...
Rui Chen   +6 more
wiley   +1 more source

The Mechanism and Potential Therapeutic Strategies of Vascular Aging

open access: yesAGING MEDICINE, EarlyView.
The phenotypes of vascular aging vary across different blood vessels. Endothelial dysfunction is observable in the endothelium of all vessels, while vascular structural remodeling primarily occurs in arteries. A decline in organ vascular density mainly affects arterioles, venules, and capillaries, whereas thrombosis predominantly occurs in the ...
Wan‐Zhou Wu   +4 more
wiley   +1 more source

Visualization of OPN‐Targeted Self‐Assembled Micelles Encapsulated With an SIRT6 Activator and Doped Indocyanine Green for Attenuating Vascular Aging

open access: yesAGING MEDICINE, EarlyView.
We developed a visualized OPN‐targeted nanodelivery system loaded with MDL800 and ICG to attenuate vascular aging via activating SIRT6 to reduce MMP9 in a mice model, providing a promising anti‐aging strategy for future clinical applications. ABSTRACT Objectives Sirtuin 6 (SIRT6) is a longevity‐associated gene with recognized therapeutic potential for ...
Yan Fang   +17 more
wiley   +1 more source

Smart Flexible Tactile Sensors: Recent Progress in Device Designs, Intelligent Algorithms, and Multidisciplinary Applications

open access: yesAdvanced Intelligent Discovery, EarlyView.
Flexible tactile sensors have considerable potential for broad application in healthcare monitoring, human–machine interfaces, and bioinspired robotics. This review explores recent progress in device design, performance optimization, and intelligent applications. It highlights how AI algorithms enhance environmental adaptability and perception accuracy
Siyuan Wang   +3 more
wiley   +1 more source

A Soft‐Tip Hydraulically Steerable Catheter for Enhanced Flexibility and Safety in Vascular Interventions

open access: yesAdvanced Intelligent Systems, EarlyView.
This study introduces a hydraulically steerable catheter with a soft tip in vascular procedures. The steering soft tip achieves a minimal diameter of 2.6 mm and supports a 180° bend. Real‐time shape and position tracking, facilitated by segmentation and endpoint detection techniques, improves navigation.
Jingyi Kang   +9 more
wiley   +1 more source

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