Results 91 to 100 of about 364,864 (311)

Predictive haemodynamics in a one-dimensional human carotid artery bifurcation. Part II: application to graft design [PDF]

, 2008
A Bayesian surrogate modelling technique is proposed that may be able to predict an optimal bypass graft configuration for patients suffering with stenosis in the internal carotid artery (ICA). At the outset, this statistical technique is considered as a
Bressloff, N. W., Kolachalama, V. B., Nair, P. B., Shearman, C. P.   +3 more
core   +1 more source

Carotid artery stenting

Swiss Medical Weekly, 2012
Atherosclerotic narrowing (stenosis) of the internal carotid artery accounts for about 10–15% of ischaemic strokes. Carotid endarterectomy (CEA) reduces the risk of stroke in patients with symptomatic stenosis and – to a lesser degree – with asymptomatic carotid stenosis.
Leo H. Bonati, Stefan T Engelter, Philippe A Lyrer   +2 more
openaire   +3 more sources

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Effect Of Mirthful Laughter On Vascular Function [PDF]

, 2010
In contrast to the well-established scientific evidence linking negative emotional states (e.g., depression, anxiety, or anger) to increased risk for cardiovascular disease, much less is known about the association between positive emotional states (e.g.,
Sugawara, Jun, Tanaka, Hirofumi, Tarumi, Takahashi   +2 more
core   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Prevalence of carotid artery disease in candidates undergoing coronary bypass graft seen at Madras Medical Mission

Sahel Medical Journal, 2013
Background: Significant carotid artery disease in candidates going for coronary artery bypass graft (CABG) increases the risk of developing peri-operative neurologic events. Therefore, a pre-operative carotid Doppler ultrasonography, which is simple, non-
Abiodun M Adeoye, Ajit S Mullassari, S R Ramkumar, K Latchumanadhas   +3 more
doaj   +1 more source

Vascular Health in American Football Players: Cardiovascular Risk Increased in Division III Players [PDF]

, 2016
Studies report that football players have high blood pressure (BP) and increased cardiovascular risk. There are over 70,000 NCAA football players and 450 Division III schools sponsor football programs, yet limited research exists on vascular health of ...
Aichele, Kristin R., Bye, Naomi L., Chavis, Lauren N., Chlad, Pamela S., Cromwell, Christina M., Evans, Rachel C., Feairheller, Deborah L., Getty, Allyson K., Hill, Jessica A., Lenzo, Jessica M., McClelland, JoAnna M., Neal, Michael P., Oakman, Joyann E., Perez, Avery N., Santaniello, Erica L., Sturgeon, Kathleen M., Thiele, Karla A., Wisdo, Tia R.   +17 more
core   +3 more sources

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Prevalence of carotid artery stenosis in ischaemic heart disease patients in Bangladesh

SAGE Open Medicine, 2019
Background: Concurrent carotid artery stenosis and ischaemic heart disease rates are increasing day by day in Bangladesh. Moreover, carotid artery stenosis has been identified as a high-risk factor for postoperative ischaemic cerebral inconvenience ...
Dipannita Adhikary, Redoy Ranjan, Sabita Mandal, Mohammad Delwer Hossain Hawlader, Dipak Kumar Mitra, Asit Baran Adhikary   +5 more
doaj   +1 more source

Genetic susceptibility loci for cardiovascular disease and their impact on atherosclerotic plaques [PDF]

, 2018
Background: Atherosclerosis is a chronic inflammatory disease in part caused by lipid uptake in the vascular wall, but the exact underlying mechanisms leading to acute myocardial infarction and stroke remain poorly understood. Large consortia identified
Asselbergs, Folkert W, Björkegrenn, Johan L.M, de Bakker, Paul I.W, de Borst, Gert J., den Ruijter, Folkert W, Dichgans, Martin, Erdmann, Jeanette, Ford, Ian, Foroughi Asl, Hassan, Haitjema, Saskia, Hedin, Ulf, Malik, Rainer, Mokry, Michal, Pasterkamp, Gerard, Paulsson-Berne, Gabrielle, Perisic, Ljubica, Samani, Nilesh J, Sattar, Naveed, Schunkert, Heribert, Siemelink, Marten A., Stott, David J., van der Laan, Sander W., van Setten, Jessica, Worrall, Bradford B   +23 more
core   +2 more sources