Results 221 to 230 of about 636,322 (300)
Peyronie's disease (PD) is a common male reproductive system disorder. The exact etiology of PD remains unclear. This study aimed to investigate molecular and cellular changes in PD using single‐cell spatial transcriptomics. Abstract Peyronie's disease (PD), commonly known as penile induration, is a prevalent male reproductive system disorder with ...
Keyuan Lou+6 more
wiley +1 more source
Semaglutide to remodel mitochondrial dynamics and mitophagy balance for vascular dementia therapy
The effects of semaglutide on IR, mitochondrial dynamics, and mitophagy in the hippocampus of BCAS mice after CCH. It was shown that semaglutide maintained the balance of mitochondrial dynamics and mitophagy by improving IR and passing through GLP‐1R/PI3K/Akt pathway, reduced hippocampal neuroinflammation and neuron loss, and thus promoted the recovery
Xiaoyan Yang+11 more
wiley +1 more source
Deciphering the panvascular immune landscape of atherosclerosis
Atherosclerosis (AS) involves inflammation in major arteries and can cause severe cardiovascular events like heart attacks and strokes, yet disease patterns vary significantly between arteries, complicating diagnosis and treatment. In this study, we integrated transcriptomic and single‐cell RNA sequencing data from AS plaques across five key arterial ...
Yiming Zhong+12 more
wiley +1 more source
Assessment of endoscopic and external approaches for frontal sinus lesions
Abstract Objectives The use of endoscopic approaches has revolutionized the management of frontal sinus (FS) lesions. However, external approaches still play a significant role in select conditions. Various factors determine the decision to utilize endoscopic or external approaches such as the lesion location, extension, and patient's characteristics ...
Moataz D. Abouammo+5 more
wiley +1 more source
Abstract Objectives Appropriate scenarios of lumbar drain (LD) use in endonasal skull base surgery is an active area of investigation. However, existing data is limited. The purpose of this study is to evaluate the robustness of the NSQIP database to characterize morbidity and complications associated with LD usage concurrent to minimally invasive ...
Benjamin F. Bitner+6 more
wiley +1 more source
Vascular Supply of Laryngeal Paragangliomas: Case Report and Systematic Review
ABSTRACT Objective Laryngeal paragangliomas are rare, highly vascularized, neuroendocrine tumors. Although surgical resection of these vascular neoplasms is associated with a known risk of significant hemorrhage, the vascular supply of laryngeal paragangliomas has been poorly characterized. Data Sources MEDLINE Ovid, Embase, Scopus, and Google Scholar.
Jane Y. Tong+3 more
wiley +1 more source
Hydrochlorothiazide plus combined exercise training provides superior benefits compared to medication alone in female spontaneously hypertensive rats subjected to ovarian hormone deprivation. This combined approach significantly reduced blood pressure variability, improved inflammatory and redox profiles, and provided functional and morphological ...
Pietra Petrica Neves+6 more
wiley +1 more source
Phenotypic Shifts in Macrophages Within Advanced Atherosclerotic Plaques in Humans
The transition from a non‐atherosclerotic to an atherosclerotic artery is associated with a shift in macrophage phenotypes. In the homeostatic environment of a non‐atherosclerotic artery, macrophages are predominantly anti‐inflammatory, anti‐atherogenic.
Barbora Muffova+11 more
wiley +1 more source
Imperative for a health‐centred focus on climate change in radiology
Summary Climate change negatively impacts individual and population‐level health through multiple pathways, including poor air quality, extreme heat and changes in infectious disease. These health effects will lead to higher health system and medical imaging utilisation.
Omar Taboun+2 more
wiley +1 more source