Results 221 to 230 of about 175,646 (300)

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Reversible cerebral vasoconstriction syndrome: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This review summarizes current insights into Reversible cerebral vasoconstriction syndrome (RCVS) diagnosis, management, and outcomes. RCVS is a cerebrovascular disorder characterized by recurrent thunderclap headaches and transient segmental vasoconstriction of cerebral arteries, typically resolving within 3 months ...
Ícaro Araújo de Sousa, Abner da Silva Machado, Arthur de Oliveira Veras, Thiago Oscar Goulart, Sarah Galassi Tatsuta, Trajano Aguiar Pires Gonçalves, Eva Rocha, Octávio Marques Pontes‐Neto   +7 more
wiley   +1 more source

The Association of Periodontitis With Cardiovascular Disease Parameters: A Synthesis of Systematic Reviews

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Focused Question What is the association of periodontal disease (PerioD) and cardiovascular diseases (CVD/CVE) as reported in existing systematic reviews (SRs)? Methods MEDLINE‐PubMed and Cochrane‐CENTRAL databases were searched. Papers that primarily evaluate cardiovascular parameters of CVD and CVE in PerioD patients compared to non‐PerioD ...
Max G. P. Schoenmakers, Lotte P. M. Weijdijk, Eveline J. S. Willems, Fridus (G. A.) van der Weijden, Dagmar Else Slot   +4 more
wiley   +1 more source

Association of low‐grade albuminuria and triple‐line pattern as markers of early peripheral vascular remodeling in adolescents with type 1 diabetes

Journal of Diabetes Investigation, EarlyView.
In adolescents with type 1 diabetes, the arterial triple‐line pattern (TLP) signals early lower extremity vascular remodeling. Low‐grade albuminuria (UACR ≥15 mg/g) independently predicts TLP, supporting the combined use of these markers to identify subclinical atherosclerosis.
Jung‐Chi Hsu, Fu‐Sung Lo, Jiann‐Shing Jeng, Wen‐Yu Tsai, Sandy Huey‐Jen Hsu, Hsiang Yang, Tien‐Jyun Chang, Ta‐Chen Su   +7 more
wiley   +1 more source

3D transparent technology displays the developmental patterns of ductus arteriosus morphology in chicken embryos before and after birth

Journal of Anatomy, EarlyView.
At the eighth week of human embryonic development, 3D transparent imaging enables clear visualization of the outflow tract's morphological features, revealing its anatomical components in detail. Abstract The ductus arteriosus (DA) is a critical fetal vascular structure that shunts blood from the pulmonary artery to the aorta, bypassing the non ...
Conghong Xu, Lidi Li, Xiu Wu, Yanli Zhang, Chuanye Wu, Juan Chen, Haihua Gao, Zhenglai Ma   +7 more
wiley   +1 more source

High cholesterol absorption efficiency interferes with bile acid metabolism and cholesterol elimination from the body

Journal of Internal Medicine, EarlyView.
Abstract Background Elevated low‐density lipoprotein (LDL) cholesterol causes atherosclerotic cardiovascular diseases. Variables of whole‐body cholesterol metabolism, for example, high cholesterol absorption efficiency, might also be atherogenic, whereas the role of bile acids is controversial.
Piia Simonen, Ingmar Wester, Jyri Lommi, Juha Sinisalo, Helena Gylling   +4 more
wiley   +1 more source

Carotid Endarterectomy in the Era of Stenting and Optimal Medical Therapy. [PDF]

Cureus
Souza Gadelha de Abreu ÍE, de Sousa Lima ME, Clares de Andrade JB.   +2 more
europepmc   +1 more source

Neurometabolic Response to Apneic Stimuli Tracks Global Grey Matter Volume Deficits in Patients With Obstructive Sleep Apnea

Journal of Sleep Research, EarlyView.
ABSTRACT Obstructive sleep apnea (OSA) has been linked to cortical atrophy and increased risk of neurodegeneration, a process potentially mediated by neurometabolic dysregulation. Recent work using high temporal‐resolution metabolic MRI found greater changes in the cerebral metabolic rate of oxygen consumption (CMRO2) during cued breath‐hold stimuli ...
Jeffrey B. Dennison, Pei‐Hsin Wu, Michael C. Langham, Richard J. Schwab, John A. Detre, Felix W. Wehrli   +5 more
wiley   +1 more source

Right posterior communicating artery aneurysm with multiple arterial stenoses and moyamoya disease: A case report. [PDF]

J Int Med Res
Liu J, Shi Z, Liu H, Wen G.
europepmc   +1 more source

Concurrent Acute Ischemic Stroke and Acute Coronary Syndrome: A Case Report on Sequential Endovascular Intervention and Peri-Procedural Antiplatelet Management with Tirofiban. [PDF]

Int Med Case Rep J
Luo H, Zhao Z, Chen Y, Li S, Wu X, Cao X, Liu X, Liu S, Liu B.   +8 more
europepmc   +1 more source