Results 101 to 110 of about 41,903 (357)

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

A Direct Carotid-Cavernous Fistula due to Penetrating Trauma by a Knitting Needle to the Temporal Region

Archives of Clinical and Experimental Surgery, 2012
Traumatic carotid-cavernous and #64257;stulas (CCF) usually occur after closed head injuries. In addition, CCFs can also be caused by penetrating injuries with stab or gunshot injuries.
Selcuk Gocmen, Murat Kutlay, Cem Atabey, Ali Kivanc Topuz, Mehmet Nusret Demircan, Murat Velioglu   +5 more
doaj   +1 more source

Traumatic Internal Carotid Artery Injuries: Do We Need a Screening Strategy? Literature Review, Case Report, and Forensic Evaluation. [PDF]

Curr Neuropharmacol, 2022
Maiese A, Frati P, Manetti AC, De Matteis A, Di Paolo M, La Russa R, Turillazzi E, Frati A, Fineschi V.   +8 more
europepmc   +1 more source

Neurosurgical Management of Self-Inflicted Cranial Crossbow Injury [PDF]

, 2018
Background Although gun-related penetrating traumatic brain injuries make up the majority of cranial missile injuries, low-velocity penetrating injuries present significant clinical difficulties that cannot necessarily be identically managed.
DeNardo, Andrew, Khairi, Saad, Kulwin, Charles G., Payner, Troy   +3 more
core   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

What does Doppler Ultrasonography Brings to the Diagnosis of Traumatic Vertebral Artery Dissection [PDF]

, 2016
Here we describe the case of a young woman with a late diagnosis of vertebral artery dissection and midbrain ischemic lesion after minor post traumatic injury.
Caruso, P, Manganotti, P, Moretti, R
core   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

ENDOVASCULAR MANAGEMENT OF LIFE-THREATENING CAROTID BLOWOUT SYNDROME AFTER OSTEORADIONECROSIS OF THE MANDIBULA — A CASE REPORT AND LITERATURE REVIEW

Angiologia e Cirurgia Vascular, 2018
Aim: Carotid blowout syndrome is a rare but devastating complication of head and neck malignancy, and is associated with a reported mortality and neurologic morbidity of 40% and 60% respectively.
Andreia Coelho, Miguel Lobo, Gustavo Coelho, Marta Azevedo, Jacinta Campos, Rita Augusto, Nuno Coelho, Ana Carolina Semião, João Pedro Ribeiro, Horácio Costa, Alexandra Canedo   +10 more
doaj   +1 more source

A Soft‐Tip Hydraulically Steerable Catheter for Enhanced Flexibility and Safety in Vascular Interventions

Advanced Intelligent Systems, EarlyView.
This study introduces a hydraulically steerable catheter with a soft tip in vascular procedures. The steering soft tip achieves a minimal diameter of 2.6 mm and supports a 180° bend. Real‐time shape and position tracking, facilitated by segmentation and endpoint detection techniques, improves navigation.
Jingyi Kang, Ye Wang, Jiayuan Liu, Zhuhao Wang, Xuan Yang, Jie Wang, Jian Wu, Guochen Ning, Boyu Zhang, Hongen Liao   +9 more
wiley   +1 more source

Origin of superior thyroid artery: under the surgeon’s knife

Jornal Vascular Brasileiro
Background The major arterial supply to the thyroid gland is from the superior and inferior thyroid arteries, arising from the external carotid artery and the thyrocervical trunk respectively.
Ranjith Sreedharan, Lalu Krishna, Ashwija Shetty   +2 more
doaj   +1 more source