Results 61 to 70 of about 141,961 (310)

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

Histological verification of atherosclerosis due to bends and bifurcations in carotid arteries predicted by hemodynamic model

open access: yesJornal Vascular Brasileiro
Background Tortuosity and bifurcations in carotid arteries alter the blood flow, causing atherosclerosis. Objectives The aim of the present study is to analyze the effect of variant vascular anatomy in the cervical region on development of ...
Rajani Singh, Richard Shane Tubbs
doaj   +1 more source

Linking cardiorespiratory fitness classification criteria to early subclinical atherosclerosis in children [PDF]

open access: yes, 2014
It is unclear if cardiorespiratory fitness (CRF) can be used as a screening tool for premature changes in carotid intima-media thickness (cIMT) in paediatric populations.
Fernhall, Bo   +6 more
core   +1 more source

Atherosclerosis of the Carotid Artery

open access: yes, 2019
Atherosclerosis, a disease affecting the large- and medium-sized vessels, is present in every human being. Atherosclerotic plaques can directly or indirectly cause obstruction of the arterial blood supply, causing ischemic damage distal from the occlusion.
Jansen, Matthijs F.   +2 more
openaire   +3 more sources

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis from ELSA‐Brasil

open access: yesArthritis Care &Research, Accepted Article.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within ELSA‐Brasil included 585 participants (86 RA, 499 controls). Longitudinal analyses were restricted to those
Patrícia Fonseca Estrada   +7 more
wiley   +1 more source

The role of biomechanics in the assessment of carotid atherosclerosis severity: a numerical approach [PDF]

open access: yes, 2018
Numerical fluid biomechanics has been proved to be an efficient tool for understanding vascular diseases including atherosclerosis. There are many evidences that atherosclerosis plaque formation and rupture are associated with blood flow ...
Bou-said, Benyebka   +4 more
core  

PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells [PDF]

open access: yes, 2019
Endothelial pro-inflammatory activation plays a pivotal role in atherosclerosis, and many pro-inflammatory and atherogenic signals converge upon mechanistic target of rapamycin (mTOR).
Althoff, Till F.   +14 more
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Regional Variation in Genetic Control of Atherosclerosis in Hyperlipidemic Mice

open access: yesG3: Genes, Genomes, Genetics, 2020
Atherosclerosis is a polygenic disorder that often affects multiple arteries. Carotid arteries are common sites for evaluating subclinical atherosclerosis, and aortic root is the standard site for quantifying atherosclerosis in mice.
Michael B. Jones   +3 more
doaj   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

open access: yesAdvanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen   +16 more
wiley   +1 more source

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