Abstract Chromosomal translocations with gene fusions are uniquely rare events in paraganglioma, mostly involving UBTF::MAML3 gene fusion. Precedent literature suggests that tumors involving MAML3 gene fusion correlate with poor clinical outcomes. Herein, we report a case of metastatic sporadic paraganglioma harboring EWSR1::CREM gene fusion in a 36 ...
Sehrish Javaid+4 more
wiley +1 more source
Main Points A subset of OPCs do not express Olig2, of which population peaks in the juvenile brain while wanes with age. Plastic changes of the brain by acute injuries or complex motor learning stop the expression of Olig2 in OPCs. Abstract Oligodendrocyte precursor cells (OPCs) are uniformly distributed in the mammalian brain; however, their function ...
Li‐Pao Fang+7 more
wiley +1 more source
Our experience in managing carotid body tumors in tertiary care center
Introduction: Carotid body tumors (CBTs), also known as paragangliomas or chemodectomas, are rare neuroendocrine neoplasms that arise near the carotid bifurcation within glomus cells derived from the embryonic neural crest. The reported incidence of CBTs
Vinay Kumar Kotavenuka+5 more
doaj +1 more source
DINs: Deep Interactive Networks for Neurofibroma Segmentation in Neurofibromatosis Type 1 on Whole-Body MRI [PDF]
Neurofibromatosis type 1 (NF1) is an autosomal dominant tumor predisposition syndrome that involves the central and peripheral nervous systems. Accurate detection and segmentation of neurofibromas are essential for assessing tumor burden and longitudinal tumor size changes.
arxiv +1 more source
Natural History and Management of Familial Paraganglioma Syndrome Type 1: Long-Term Data from a Large Family [PDF]
Head and neck paragangliomas are the most common clinical features of familial paraganglioma syndrome type 1 caused by succinate dehydrogenase complex subunit D (SDHD) mutation. The clinical management of this syndrome is still unclear.
Cantisani, Vito+12 more
core +1 more source
Accessory thyroid gland at carotid bifurcation presenting as a carotid body tumor: case report and review of the literature [PDF]
Patients with carotid body tumors referred to vascular surgeons usually undergo magnetic resonance imaging (MRI) as part of the workup. We present a case report of a 39-year-old woman with a presumed carotid body tumor, as was expected from clinical and ...
Hollander, Evert-Jan F+2 more
core +1 more source
Computational hemodynamics in arteries with the one-dimensional augmented fluid-structure interaction system: viscoelastic parameters estimation and comparison with in-vivo data [PDF]
Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body hemodynamics, the viscoelastic properties of vessel walls are a key aspect to be taken into account as they play an essential ...
arxiv +1 more source
EXPERIENCE OF SURGICAL TREATMENT OF THE CAROTID BODY TUMOR AND TUMORS WITH INVASION AT THE CAROTID VESSELS [PDF]
The analysis of the structure and results of surgical treatment of 72 patients who were hospitalized in the department of vascular surgery Lviv regional hospital for the period 1995 to 2017.
Kobza, Ihor, Savchenko, Arkadiy
core +3 more sources
A Review on End-To-End Methods for Brain Tumor Segmentation and Overall Survival Prediction [PDF]
Brain tumor segmentation intends to delineate tumor tissues from healthy brain tissues. The tumor tissues include necrosis, peritumoral edema, and active tumor. In contrast, healthy brain tissues include white matter, gray matter, and cerebrospinal fluid. The MRI based brain tumor segmentation research is gaining popularity as; 1. It does not irradiate
arxiv +1 more source
TrAp: a Tree Approach for Fingerprinting Subclonal Tumor Composition [PDF]
Revealing the clonal composition of a single tumor is essential for identifying cell subpopulations with metastatic potential in primary tumors or with resistance to therapies in metastatic tumors. Sequencing technologies provide an overview of an aggregate of numerous cells, rather than subclonal-specific quantification of aberrations such as single ...
arxiv +1 more source