Results 101 to 110 of about 286,425 (314)

PCBP2 Regulates p16INK4a‐Dependent Cellular Senescence in Response to Iron

Aging Cell, Volume 24, Issue 12, December 2025.
PCBP2 induces cellular senescence by modulating the expression of p16INK4a and CD40 in response to iron. PCBP2 activates p16INK4a via the functional SNP rs1333046 on the atherosclerosis‐associated CDKN2A/B locus. ABSTRACT Recently, we have identified rs1333046 as one of the candidate functional single nucleotide polymorphisms (fSNPs) on the ...
Shaoyang Yan, Lili Lu, Yuwei Wu, Zewen Du, Ebin Johny, Partha Dutta, Gang Li   +6 more
wiley   +1 more source

Carotid endarterectomy for carotid stenosis: audit at a tertiary referral centre [PDF]

, 1999
Prospective randomised controlled trials performed in North America and Europe have demonstrated that the risk of future stroke or death is substantially reduced by performing carotid endarterectomy in symptomatic patients who have severe carotid ...
Cheng, SWK, Lau, H
core  

In the Spotlight [PDF]

, 2017
In September, 10 advanced practice nurses from the Department of Surgery gathered for a lunchtime kick-off meeting to form a Nurse Practitioners (NPs) & Physician Assistants (PAs) Professionalism and Scholarship Working Group.

core   +2 more sources

Impact of deep learning based reconstruction algorithms on CT radiomic features of carotid plaques

Journal of Applied Clinical Medical Physics, Volume 26, Issue 11, November 2025.
Abstract Background Radiomics is increasingly applied in carotid plaques analysis to evaluate plaque characteristics and predict cardiovascular risk. However, the influence of different image reconstruction algorithms, particularly deep learning reconstruction (DLIR) and adaptive statistical iterative reconstruction‐Veo (ASIR‐V), on the reproducibility
Hanzhe Wang, Jingkai Xu, Chengeng Ye, Aiyun Sun, Jinjin Liu, Shuyang Wang, Xiangwu Zheng, Guoquan Cao   +7 more
wiley   +1 more source

Clinical Studies Target Fewer Complications, Better Outcomes for Vascular Surgery [PDF]

, 2017
Two studies at the Jefferson Vascular Center (JVC) are assessing innovative methods to reduce risk of complications — and increase positive outcomes — for vascular surgery patients. Here, Paul DiMuzio, MD, FACS, William M. Measey Professor of Surgery and

core   +1 more source

Long-Term Follow-Up Study of Endarterectomy Versus Angioplasty in Patients With Symptomatic Severe Carotid Stenosis Trial

Stroke, 2014
Background and Purpose— We aimed at comparing the long-term benefit–risk balance of carotid stenting versus endarterectomy for symptomatic carotid stenosis.
J. Mas, C. Arquizan, D. Calvet, A. Viguier, J. Albucher, P. Piquet, P. Garnier, F. Viader, M. Giroud, H. Hosseini, G. Hinzelin, P. Favrole, H. Hénon, J. Neau, X. Ducrocq, R. Padovani, L. Milandre, F. Rouanet, V. Wolff, D. Saudeau, M. Mahagne, D. Sablot, P. Amarenco, V. Larrue, B. Beyssen, D. Leys, T. Moulin, M. Lièvre, G. Chatellier   +28 more
semanticscholar   +1 more source

Advanced Image‐Guidance and Surgical‐Navigation Techniques for Real‐Time Visualized Surgery

Advanced Science, Volume 12, Issue 41, November 6, 2025.
This review comprehensively summarizes advances in surgical navigation, covering both established and emerging intraoperative imaging technologies. It highlights mechanisms, advantages, limitations, and clinical applications, while emphasizing interdisciplinary collaboration.
Xiaoxiao Fan, Xiaolong Liu, Qiming Xia, Guoqiao Chen, Jiaxi Cheng, Zhaoqi Shi, Yifeng Fang, Parikshit Asutosh Khadaroo, Jun Qian, Hui Lin   +9 more
wiley   +1 more source

Carotid stenting for irradiation-associated carotid stenosis 3 years after previous carotid endarterectomy [PDF]

, 2003
Extracranial carotid stenosis is a known complication of external irradiation to the head and neck region. We report on a patient with previous carotid endarterectomy for irradiation-associated carotid stenosis. This patient developed symptomatic carotid
Cheng, PW, Cheng, SWK, Ting, ACW
core  

The Neurological Morbidity of Carotid Revascularisation: Using Markers of Cellular Brain Injury to Compare CEA and CAS [PDF]

, 2007
AimThis comparative study attempts to evaluate the profile of S-100β and Neuron-Specific Enolase (NSE), biomarkers of brain injury, in patients undergoing carotid endarterectomy (CEA) and carotid artery stenting (CAS) and to correlate this with ...
Athanasiou, T., Brightwell, R.E., Cheshire, N.J.W., Hamady, M., Sherwood, R.A.   +4 more
core   +4 more sources

In an older‐age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p‐tau217

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Asymptomatic extracranial carotid atherosclerotic disease (aECAD) has been associated with Alzheimer's disease (AD), but the earliest cognitive deficits in this hallmark vascular population are largely unknown. METHODS A total of 182 participants 50–85 years of age with ≥2 vascular comorbidities with/without aECAD were evaluated ...
Summan Zahra, Scott R. French, Juan C. Arias, Madeline Ally, Haley Wiskoski, Cris Escareno, Emma Heitkamp, Franchell Vazquez, Madison Hillis, Gavin Culwell, Karthik Ainapurapu, Caronae M. Howell, Kevin Johnson, Deniz Karakay, Karthik Rayasam, Lindsay Taylor, Cody Kraemer, Luis Leon, Scott Berman, Federico Yanquez, Joshua Balderman, Joseph Sabat, Olivia Hung, Layla Lucas, Edward J. Bedrick, Francesca Vitali, Raza Mushtaq, Maria Altbach, Theodore P. Trouard, Ali Bilgin, Eric M. Reiman, Gene E. Alexander, Craig C. Weinkauf   +32 more
wiley   +1 more source