Results 191 to 200 of about 125,875 (345)

Rationale and design of a multicenter randomized study for evaluating vascular function under uric acid control using the xanthine oxidase inhibitor, febuxostat : the PRIZE study [PDF]

, 2020
Background: Xanthine oxidase inhibitors are anti-hyperuricemic drugs that decrease serum uric acid levels by inhibiting its synthesis. Xanthine oxidase is also recognized as a pivotal enzyme in the production of oxidative stress.
Ako, Junya, Bando, Yasuko K., Eguchi, Kazuo, Higashi, Yukihito, Inoue, Teruo, Ishizaka, Nobukazu, Ishizu, Tomoko, Kanzaki, Yumiko, Kuroyanagi, Takanori, Maemura, Koji, Murohara, Toyoaki, Node, Koichi, Ohishi, Mitsuru, Oyama, Jun‑ichi, Sata, Masataka, Sato, Yasunori, Taguchi, Isao, Tanaka, Atsushi, Teragawa, Hiroki, Tomiyama, Hirofumi, Ueda, Shinichiro, Yamada, Hirotsugu   +21 more
core  

Metformin use in women with polycystic ovary syndrome (PCOS): Opportunities, benefits, and clinical challenges

Diabetes, Obesity and Metabolism, Volume 27, Issue S3, Page 31-47, June 2025.
Abstract Metformin, a synthetic biguanide, is widely used to manage type 2 diabetes, and is commonly prescribed in polycystic ovary syndrome (PCOS) to address insulin resistance and associated metabolic and reproductive disturbances. PCOS is characterised by hormonal imbalances such as hyperandrogenism and anovulation, metabolic abnormalities including
Saeede Saadati, Taitum Mason, Rasoul Godini, Eszter Vanky, Helena Teede, Aya Mousa   +5 more
wiley   +1 more source

Cardiac Mass and Function, Carotid Artery Intima-Media Thickness, and Lipoprotein Levels in Growth Hormone-Deficient Adolescents [PDF]

, 2001
Roberto Lanes
openalex   +1 more source

Investigation of carotid intima-media thickness in patients with schizophrenia

BMC Psychiatry
Abstract Background Patients with schizophrenia (SCZ) have a higher risk of cardiovascular diseases than the average population. Early diagnosis of SCZ patients with subclinical atherosclerosis is great importance in reducing cardiovascular morbidity and mortality.
Yaşar Kapıcı, Olga Bayar Kapıcı, Sabri Abuş, Mehmet Hamdi Örüm, Selçuk Ayhan, Mehmet Bozkurt, Bilal Özer, Atilla Tekin   +7 more
openaire   +3 more sources

TcMAC21 mouse model recapitulates abnormal vascular physiology observed in humans with Down syndrome

Physiological Reports, Volume 13, Issue 11, June 2025.
Abstract People with Down syndrome (DS) have abnormal vascular physiology, demonstrated by low systolic blood pressure (BP) and low aortic stiffness that are accompanied by endothelial dysfunction. The TcMAC21 mouse model of DS has many features observed in people with DS, although vascular physiology has not been studied.
Xiangyu Zheng, Mostafa Sabouri, Bryan J. Irwin, Joseph Bernardo, Daniel R. Machin   +4 more
wiley   +1 more source

Low-Dose Metoprolol CR/XL and Fluvastatin Slow Progression of Carotid Intima-Media Thickness [PDF]

, 2001
Bo Hedblad, John Wikstrand, Lars Janzon, Hans Wedel, G. Berglund   +4 more
openalex   +1 more source

Long‐term risk and characteristics of cerebrovascular events after upper body radiotherapy among childhood cancer survivors in the DCCSS‐LATER cohort

International Journal of Cancer, Volume 156, Issue 10, Page 1858-1872, 15 May 2025.
What's new? Due to the nature of cancer treatments, childhood cancer survivors have an increased risk of serious adverse events later in life. Here, the authors examined the incidence of cerebrovascular events (CVEs) among childhood cancer survivors who had received upper body radiotherapy.
Lisanne C. Verbruggen, Judith L. Kok, Leontien C. M. Kremer, Geert O. Janssens, Paul J. Nederkoorn, Adriaan Penson, A. Birgitta Versluijs, Andrica C. H. de Vries, Ardine M. J. Reedijk, Dorine Bresters, Eelco W. Hoving, Eline van Dulmen‐den Broeder, Jacqueline J. Loonen, Judith de Bont, Joyce Wilbers, Marloes Louwerens, Margriet van der Heiden‐van der Loo, Marry M. van den Heuvel‐Eibrink, Saskia M. F. Pluijm, Sebastian J. C. M. M. Neggers, Wim J. E. Tissing, Yvo B. W. E. M. Roos, Cécile M. Ronckers, Jop C. Teepen, Helena J. H. van der Pal, on behalf of the DCCSS‐LATER consortium, Jaap den Hartogh, Floor van Leeuwen, Irma van Dijk   +28 more
wiley   +1 more source

Prognostic implications of intima-media thickness and plaques in the carotid and femoral arteries in patients with stable angina pectoris [PDF]

, 2001
Claes Held
openalex   +1 more source

Mannheim Carotid Intima-Media Thickness and Plaque Consensus (2004–2006–2011)

Cerebrovascular Diseases, 2012
P. Touboul, M. Hennerici, S. Meairs, H. Adams, P. Amarenco, N. Bornstein, L. Csiba, M. Desvarieux, S. Ebrahim, R. Hernandez, M. Jaff, S. Kownator, T. Naqvi, P. Prati, T. Rundek, M. Sitzer, U. Schminke, J. Tardif, A. Taylor, E. Vicaut, K. Woo   +20 more
semanticscholar   +1 more source

Plasminogen Activator Inhibitor 1 Controls Abdominal Aortic Aneurism Formation via the Modulation of TGF‐β/Smad2/3 Signaling in Mice

The FASEB Journal, Volume 39, Issue 9, 15 May 2025.
Graphical illustration of the mechanism underlying the acceleration of plasminogen activator inhibitor1 deletion‐mediated abdominal aneurysm formation in mice undergoing calcium chloride2 induction surgery. Genetic intervention targeted toward plasminogen activator inhibitor1 accelerated AAA formation via the modulation of TGF‐β/Smad2/3 signaling in ...
Mantong Zhao, Lina Hu, Zhuo Lin, Xueling Yue, Xintong Zheng, Meiling Piao, Xianglan Jin, Limei Piao, Rihua Cui, Meilan Liu, Xian Wu Cheng   +10 more
wiley   +1 more source