Results 81 to 90 of about 18,178 (229)

Cerebral in situ ischemic postconditioning: From bench to bedside and beyond

open access: yesNeuroprotection, Volume 4, Issue 1, Page 48-64, March 2026.
This review explores the translational potential of in situ ischemic postconditioning in acute ischemic stroke. Preclinical and clinical evidence is summarized to highlight its promise as a neuroprotective strategy in the era of endovascular therapy.
Xiao Jiang   +4 more
wiley   +1 more source

Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries [PDF]

open access: yes, 2011
<p><b>Objective:</b> We have previously demonstrated that bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs), is effective in reducing neointimal formation in rodent models of vascular injury by reducing smooth ...
Baker, A.H.   +10 more
core   +1 more source

Nanomedicine Targeting Macrophage Immunometabolism in Atherosclerosis: Mechanisms and Therapeutic Prospects

open access: yesOrgan Medicine, Volume 3, Issue 1, Page 27-53, March 2026.
ABSTRACT Atherosclerosis, a chronic inflammatory–metabolic disorder, remains a leading cause of cardiovascular morbidity worldwide. This review explores the emerging paradigm of nanomedicine‐based targeting of macrophage immunometabolic reprogramming as a potentially transformative strategy for atherosclerosis treatment.
Zhenyu Liu, Wenfan Yang, Na Wang, Ya Wu
wiley   +1 more source

Inhibitory Effect of Curcumin on Artery Restenosis Following Carotid Endarterectomy and Its Associated Mechanism in vitro and in vivo

open access: yesDrug Design, Development and Therapy, 2020
Dapeng Zhang,1 Yanhui Yang,2 Yuanchao Li,1 Guodong Zhang,1 Zhenguo Cheng1 1Neurosurgery Department, Xinxiang Central Hospital, Xinxiang, Henan Province 453000, People’s Republic of China; 2Color Ultrasonic Room, People’s Hospital of Huixian ...
Zhang D, Yang Y, Li Y, Zhang G, Cheng Z
doaj  

Restenosis after carotid endarterectomy.

open access: yesInternational journal of clinical practice, 2007
Multiple randomised trials over the last decade for both symptomatic and asymptomatic carotid stenosis have proven the efficacy of carotid endarterectomy (CE) in reducing the risk of stroke. The long-term patency of the carotid artery after CE is an important factor in the success of the operation. The incidence of recurrent carotid stenosis (excluding
H, Sadideen   +2 more
openaire   +1 more source

Carotid Endarterectomy for Treatment of Instent Restenosis [PDF]

open access: yesJournal of Vascular Surgery, 2010
In-stent restenosis (ISR) after carotid angioplasty and stenting is becoming evident as more patients undergo carotid stenting and duplex scan surveillance. While redo endovascular therapy has been immediately successful, recurrent stenosis remains a problem. The ideal management of ISR has not been determined.
Gonzalez, Alberto   +3 more
openaire   +3 more sources

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo   +22 more
wiley   +1 more source

Severe Supravalvular Aortic Stenosis Treated With Double Patch Aortoplasty: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Severe supravalvular aortic stenosis in a young patient is a rare but critical condition requiring timely diagnosis and intervention. We report a 15‐year‐old girl presenting with exertional dyspnea, chest pain, and palpitations. Echocardiography and multidetector computed tomography (MDCT) confirmed severe supravalvular aortic stenosis ...
Birat Kadel   +4 more
wiley   +1 more source

Heyde Syndrome: A Literature Review

open access: yesHealth Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Heyde syndrome, a triad of anemia from gastrointestinal (GI) bleeding, aortic valve stenosis, and acquired von Willebrand syndrome, primarily affects individuals over 65. Management requires a multidisciplinary approach, including medical therapy, endoscopic intervention, and valve replacement.
Yashika Gupta   +12 more
wiley   +1 more source

Long-term Outcomes of Carotid Artery Stenting for Radiation-Associated Stenosis

open access: yesBiomedical Journal, 2013
Background: In Taiwan, the prevalence of head and neck cancer is relatively high. Because radiation-associated carotid stenosis is a significant risk factor for stroke, carotid artery stenting (CAS), instead of carotid endarterectomy, is indicated in ...
Min-Ping Huang   +7 more
doaj   +1 more source

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