Results 161 to 170 of about 554,694 (315)

The role of acid‐base balance in cerebrovascular and ventilatory responses to CO2 during 10 h normobaric hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay   +3 more
wiley   +1 more source

Elevated carotid body tonic activity contributes to ventilatory acclimatization and de‐acclimatization to high altitude at rest and during exercise

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Participants spent 13 days at high altitude (3800 m), where the reduced inspired oxygen pressure (↓PiO2$ \downarrow {P_{{\mathrm{i}}{{\mathrm{O}}_2}}}$) which elicited ventilatory acclimatization and increased inhibition of ventilation by transient hyperoxia (ΔV̇E$\Delta {\dot V_{\mathrm{E}}}$).
Ayechew A. Getu   +6 more
wiley   +1 more source

Histology and immunohistochemistry of the human carotid sinus nerve. [PDF]

open access: yesAnat Cell Biol, 2023
Bryant D   +9 more
europepmc   +1 more source

Role of reactive oxygen species in mediating peripheral hypoxic vasodilation and sympathoexcitation at high altitude

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr   +15 more
wiley   +1 more source

Non‐Contrast Assessment of Blood–Brain Barrier Permeability to Water: Improved Signal Modeling and Data Acquisition

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 4, Page 1998-2008, April 2026.
ABSTRACT Purpose Water‐extraction‐with‐phase‐contrast‐arterial‐spin‐tagging (WEPCAST) MRI is a non‐contrast method to estimate the blood–brain barrier (BBB) permeability to water. Similar to other arterial‐spin‐labeling (ASL) based techniques, signal‐to‐noise ratio is a limitation.
Wen Shi   +11 more
wiley   +1 more source

Metabolic Stroke: Atypical Presentation of Succinic Semialdehyde Dehydrogenase Deficiency

open access: yesJIMD Reports, Volume 67, Issue 2, March 2026.
ABSTRACT Succinic semialdehyde dehydrogenase (SSADH) deficiency is a rare autosomal recessive neurometabolic disorder caused by biallelic pathogenic variants in ALDH5A1, encoding the mitochondrial enzyme SSADH. This enzyme catalyses the conversion of succinic semialdehyde to succinic acid in the γ‐aminobutyric acid (GABA) degradation pathway.
Sharmila Kiss   +10 more
wiley   +1 more source

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