Results 191 to 200 of about 271,709 (284)

Posture‐Related Regional Homogeneity Abnormalities in Cerebral Small Vessel Disease: A Multi‐Position MRI Study

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Patients with CSVD showed higher upright ReHo in anterior cingulate gyrus (ACG) than NCs, and supine‐upright comparison revealed widespread ReHo alterations. Upright ACG ReHo and posture‐related ReHo changes in the hippocampus, putamen, and calcarine cortex were associated with poorer cognition and greater CSVD burden, suggesting that upright imaging ...
Yukun Zhang   +13 more
wiley   +1 more source

Oligodendrocyte‐Targeted SGK1.1 Inhibition Alleviates White Matter Injury and Cognitive Impairment in Alzheimer's Disease via Modulation of HDAC2 Phosphorylation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
We found an early Sgk1.1 mRNA upregulation within oligodendrocyte‐lineage cells of 5 × FAD mice, implicating SGK1.1 signaling as an early driver of myelin pathology. Mechanistically, SGK1.1 promotes HDAC2 phosphorylation at S422/S424, thereby impairing oligodendrocyte maturation.
Shiji Deng   +13 more
wiley   +1 more source

Numerical Aspects of Turbulent Blood Flow in Aorta: A Systematic Review

open access: yesEngineering Reports, Volume 8, Issue 9, September 2026.
The aim of this systematic review is to systematize the methodological approaches used in the state‐of‐the‐art literature, including the choice of turbulence models, validation methods, as well as the identification of the main hemodynamic parameters characterizing turbulent flow.
Nikita Skripka, Alex G. Kuchumov
wiley   +1 more source

Transcranial Color‐Coded Duplex Sonography in Large‐Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report

open access: yesJournal of Clinical Ultrasound, Volume 54, Issue 7, Page 1710-1716, September 2026.
This case illustrates sequential intracranial occlusions in large‐vessel vasculitis compatible with Takayasu arteritis preserving perfusion through robust collateral pathways. Transcranial color‐coded duplex sonography identified characteristic blunted flow patterns and focal turbulence, underscoring its value in detecting hemodynamic compromise beyond
Maria Júnia Lira e Silva   +4 more
wiley   +1 more source

Neurocardiology: Brain–Heart Interactions in the Heart

open access: yesMedComm, Volume 7, Issue 9, September 2026.
The heart and brain maintain systemic homeostasis through bidirectional communication involving neural, biochemical, and mechanical pathways. Dysregulation of these pathways contributes to a spectrum of conditions involving heart–brain interactions, including Takotsubo syndrome, the epileptic heart, stroke–heart syndrome, heart failure, cardiac ...
Wentao Wang   +3 more
wiley   +1 more source

Unraveling the Metabolic‐Cardiovascular Disease Nexus: An Epidemiological Network Analysis Identifies Central Indicators

open access: yesMedComm, Volume 7, Issue 9, September 2026.
In the STONE cohort with 4752 Shanghai citizens, the CardioMet12 CVD scoring system was established by clustering individuals across seven metabolic dimensions. Based on analysis from Chinese and US epidemiological cohorts and network analysis, CardioMet12 emerges as a robust metric that considers the complex interplay among metabolic disorders ...
Xin‐yi Cai   +10 more
wiley   +1 more source

Medical Management and Revascularization for Asymptomatic Carotid Stenosis. [PDF]

open access: yesN Engl J Med
Brott TG   +44 more
europepmc   +1 more source

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