Results 101 to 110 of about 2,158,108 (173)

Hypoxia‐induced vulnerability of the somatosensory nervous system

The Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

A Rare Case of Carotid Web Presenting with Ischemic Stroke in a Young Woman and a Brief Review of the Literature

Case Reports in Medicine, 2018
Carotid web is a radiological description of a shelf-like intraluminal filling defect in the carotid bulb. It is histologically defined as atypical fibromuscular dysplasia (FMD), with abnormal fibrosis and smooth muscle cell hyperplasia in the tunica ...
Kyaw Kyaw, Htun Latt, Sammy San Myint Aung, Jay Babu, Rajesh Rangaswamy   +4 more
doaj   +1 more source

Targeting Microglial HDAC5 Suppresses NLRP3 Inflammation via NF‐κB Deacetylation to Alleviate Ischemic Brain Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Cerebral ischemia/reperfusion induced HDAC5 upregulation in microglia. Elevated HDAC5 promoted NLRP3‐mediated neuroinflammation via NF‐κB p65 deacetylation. RGD‐EV:miR‐9‐5p delivery suppressed microglial HDAC5 and attenuated ischemic brain injury. ABSTRACT Objective Histone deacetylases are implicated in ischemic stroke, yet the role of HDAC5 remains ...
Ru‐Yu Liang, Jia‐Qi Zhang, Tian‐Yi Jiang, Li‐Qing Tao, Wen She, Zhou‐Na Sun, Cui Qi, Jun Gao   +7 more
wiley   +1 more source

Converting Equol Nonproducers to Producers: A Systematic Review of Randomized Clinical Trials

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This systematic review, following PRISMA guidelines, screened 503 records identified through PubMed, Embase, Web of Science, and ClinicalTrials.gov, of which 12 randomized clinical trials (n = 730, 85.5% female) met inclusion criteria. Interventions included soy isoflavones alone, probiotics, or prebiotics combined with soy, fermented soy products ...
Jiatong Li, Mengyi Li, Saied Aboushanab, Mark Ebeid, Rieko Hatanaka, Miho Iida, Masato Takase, Ian Jacobs, Arnur Gusmanov, Aya Hirata, Naoko Miyagawa, Naoki Nakaya, Daisuke Sugiyama, Curtis Tilves, Atsushi Hozawa, Xingnan Li, Noel T. Mueller, Panayiotis V. Benos, Akira Sekikawa   +18 more
wiley   +1 more source

Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques: Meta-Analysis of Individual Patient Data [PDF]

, 2019
ObjectivesThe goal of this study was to compare the risk of stroke between patients with carotid artery disease with and without the presence of intraplaque hemorrhage (IPH) on magnetic resonance imaging.BackgroundIPH in carotid stenosis increases the ...
Singh, Navneet, Yoshida, Kazumichi, Moody, Alan R., Yamagata, Sen, Schinner, Regina, Kooi, M. Eline; id_orcid, Saam, Tobias, Kooi, M. Eline, Kwee, Robert M., Schindler, Andreas, Altaf, Nishaf, Poppert, Holger, Simpson, Richard J., Esposito-Bauer, Lorena, Kurosaki, Yoshitaka, Bonati, Leo H., Maggisano, Robert, Auer, Dorothee P., Miyamoto, Susumu, Hosseini, Akram A.   +19 more
core   +1 more source

The Natural History of Residual and Recurrent Disease in Advanced Juvenile Nasopharyngeal Angiofibroma: A Systematic Review

The Laryngoscope, Volume 136, Issue 10, Page 4130-4138, October 2026.
Residual and recurrent disease in advanced juvenile nasopharyngeal angiofibromas (JNAs) demonstrate spontaneous involution, reduction in size, or long‐term stability following initial treatment in 95% of patients. In this systematic review of 131 patients with advanced JNA, only 2% of patients demonstrated disease progression during surveillance, but ...
Shivani Angelique Kumar, Peter Petocz, Raewyn G. Campbell   +2 more
wiley   +1 more source

Spontaneous carotid artery dissection-associated medial changes in a selected autopsy population [PDF]

, 2008
Spontaneous carotid artery dissection (SCAD) is a major cause of stroke in young adults, yet its pathogenesis remains unclear. Hereditary connective tissue diseases, hormonal influences, sympathomimetic drugs or upper respiratory tract infections may ...
Frickey, Nathalie Alexandra
core  

Carotid plaque stress analysis by fluid structure interaction based on in-vivo MRI: Implications to plaque vulnerability assessment [PDF]

, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 2010.Stroke is one of the leading causes of death in the world, resulting mostly from the sudden rupture of atherosclerotic plaques.
Gao, Hao
core   +2 more sources

Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease

MedComm, Volume 7, Issue 10, October 2026.
NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang, Fangjiaqi Wei, Mengdi Qu, Yuwen Shao, Tingye Xu, Darko Stojkov, Hans‐Uwe Simon, Ben Huang, Changhong Miao, Hao Zhang   +9 more
wiley   +1 more source

Low Diagnostic Accuracy and Moderate Inter‐Rater Agreement Among Specialists in Identifying Carotid Artery Webs on Imaging

Clinical Neuroimaging
Background Carotid artery web (CW), an intimal variant of fibromuscular dysplasia, is an underrecognized cause of ischemic stroke associated with high recurrence rates. Its subtle imaging features often lead to underdiagnosis.
Farhan Khan, Dylan Wolman, Narendra Kala, Elizabeth Perelstein, Krisztina Moldovan, Radmehr Torabi, Shadi Yaghi   +6 more
doaj   +1 more source