Results 51 to 60 of about 18,605 (231)

Real‐world characteristics and treatment of cardiac transthyretin amyloidosis: A multicentre, observational study

ESC Heart Failure, Volume 12, Issue 2, Page 1203-1216, April 2025.
The 366 patients diagnosed with transthyretin amyloidosis cardiomyopathy (ATTR‐CM) were analyzed regarding their clinical characteristics in the first year after approval of tafamidis 61 mg for ATTR‐CM in Germany. Nearly two‐thirds of the patients were in an advanced disease stage and 64% met the key criteria of the “Transthyretin Amyloidosis ...
Richard J. Nies, Svenja Ney, Ingrid Kindermann, Yvonne Bewarder, Angela Zimmer, Fabian Knebel, Katrin Hahn, Sebastian Spethmann, Peter Luedike, Lars Michel, Tienush Rassaf, Maria Papathanasiou, Stefan Störk, Vladimir Cejka, Amin Polzin, Fabian Voss, Malte Kelm, Bernhard Unsöld, Christine Meindl, Michael Paulus, Ali Yilmaz, Bishwas Chamling, Caroline Morbach, Roman Pfister   +23 more
wiley   +1 more source

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source

Sex-Specific Size Analysis of Carpal Bones: Implications for Orthopedic Biomedical Device Design and Therapy Planning

Life
Consideration of the individual carpal bone characteristics of the wrist plays a key role in well-functioning biomedical devices and successful surgical procedures.
Malte Asseln, Valentin Quack, Roman Michalik, Björn Rath, Frank Hildebrand, Filippo Migliorini, Jörg Eschweiler   +6 more
doaj   +1 more source

THE RHEUMATOID HAND (Part II)

Современная ревматология, 2010
The chronic inflammatory process characteristic of rheumatic arthritis (RA) leads over time to irreversible disorders caused by destruction of the articular cartilage and bones and lesions to the ligaments and tendons.
Yu A Olyunin, A V Smirnov, Yu A Olyunin, A V Smirnov   +3 more
doaj   +1 more source

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

Nonvascularized Iliac Crest Autograft for Wrist and Hand Reconstructions: A Report of Two Clinical Cases and Literature Review

Journal of Orthopaedic Case Reports
Introduction: Bone defects of the hand and wrist may result from trauma or tumor resection and represent a reconstructive challenge due to the complex anatomy and functional demands of this region.
Joana Páscoa Pinheiro, André Spranger, Paulo Almeida, José Portela, Joaquim Soares do Brito   +4 more
doaj   +1 more source

Agreement of Multimodal Large Language Models and Novice Readers With Expert-Based Radiographic Scoring of Presumptive Septic Carpal Arthritis in Calves. [PDF]

Vet Radiol Ultrasound
ABSTRACT Septic arthritis is an important cause of morbidity in calves, and radiographic interpretation may vary between observers, especially when structured scoring systems are used by less experienced readers. This single‐center retrospective reader study evaluated whether general‐purpose multimodal large language models (LLMs) could support rubric ...
Bedir AG, Modoğlu E, Kartal T, Kibar B, Gökhan Şenocak M, Orhun ÖT, Turgut F, Ersöz U, Kocaman Y, Akçora Y, Okur S, Yanmaz LE.   +11 more
europepmc   +2 more sources

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source

Comparison of bone age assessment using manual Greulich and Pyle method versus automated BoneXpert method in South African children

South African Journal of Radiology
Background: The Greulich and Pyle (GP) method is the most commonly used manual bone age assessment method but it is associated with interrater variability.
Radhiya Minty, Nasreen Mahomed, Nicole van Wyk, Gopolang Mndebele, Zarina Lockhat, Ashesh Ranchod   +5 more
doaj   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

Journal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini, Riccardo Picasso, Antonio Corvino, Federico Zaottini   +3 more
wiley   +1 more source