Results 61 to 70 of about 1,641,333 (304)

Modelling the anabolic response of bone using a cell population model [PDF]

open access: yesJ Theor Biol 307 (2012) 42-52, 2011
To maintain bone mass during bone remodelling, coupling is required between bone resorption and bone formation. This coordination is achieved by a network of autocrine and paracrine signalling molecules between cells of the osteoclast lineage and cells of the osteoblastic lineage.
arxiv   +1 more source

Hereditary Multiple Osteochondromas and Acute Lymphoblastic Leukemia: A Possible Role for EXT1 and EXT2 in Hematopoietic Malignancies

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hereditary multiple osteochondromas (HMO) is an autosomal dominant disorder caused by heterozygous deleterious variants in the EXT1 or EXT2 genes. While the clinical core phenotype is well established and mainly consists of bone deformities, limb length discrepancies, multiple benign bone neoplasms, and increased risk of chondrosarcoma, the ...
Francesco Comisi   +7 more
wiley   +1 more source

Fractures and Dislocations of the Carpal Bones [PDF]

open access: yesClinics in Sports Medicine, 1986
The most common wrist fractures in athletes are fractures of the scaphoid and fractures of the hook of the hamate. Accurate diagnosis and conservative treatment are extremely important. A physician should not compromise principles of treatment for a rapid return of the athlete to competition, because all too often this will jeopardize eventual recovery
Norman P. Zemel, Herbert H. Stark
openaire   +3 more sources

Is cranial anatomy indicative of fossoriality? A case study of the mammaliaform Hadrocodium wui

open access: yesThe Anatomical Record, EarlyView.
Abstract Determining the ecology of fossil species presents considerable challenges due to the often fragmentary preservation of specimens. The mammaliaform Hadrocodium wui from the Jurassic of China is known only from the cranium and mandible but may have had a fossorial lifestyle.
Molly Tumelty, Stephan Lautenschlager
wiley   +1 more source

Attention-Guided Discriminative Region Localization and Label Distribution Learning for Bone Age Assessment [PDF]

open access: yesarXiv, 2020
Bone age assessment (BAA) is clinically important as it can be used to diagnose endocrine and metabolic disorders during child development. Existing deep learning based methods for classifying bone age use the global image as input, or exploit local information by annotating extra bounding boxes or key points.
arxiv  

Review of the anatomical basis for predicting plutonium alpha particle radiation induced osteogenic cancers

open access: yesThe Anatomical Record, EarlyView.
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley   +1 more source

Multicentric Carpo-Tarsal Osteolysis

open access: yesJournal of the Belgian Society of Radiology, 2023
MCTO is a rare autosomal-dominant inherited disorder that causes bone destruction and deformity of the appendicular bones in children, with the carpal and tarsal bones severely affected.
Lea Tannouri, Paolo Simoni
doaj   +1 more source

Breast Cancer Induced Bone Osteolysis Prediction Using Temporal Variational Auto-Encoders [PDF]

open access: yesarXiv, 2022
Objective and Impact Statement. We adopt a deep learning model for bone osteolysis prediction on computed tomography (CT) images of murine breast cancer bone metastases. Given the bone CT scans at previous time steps, the model incorporates the bone-cancer interactions learned from the sequential images and generates future CT images.
arxiv  

The role of the PTHrP/Ihh feedback loop in the unusual growth plate location in mammalian metatarsals and pisiforms

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Longitudinal skeletal growth takes place in the cartilaginous growth plates. While growth plates are found at either end of conventional long bones, they occur at a variety of locations in the mammalian skeleton. For example, the metacarpals and metatarsals (MT) in the hands and feet form only a single growth plate at one end, and ...
Philip L. Reno   +4 more
wiley   +1 more source

Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone   +8 more
wiley   +1 more source

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