Results 41 to 50 of about 36,356 (198)

Uncoupling TGFβ1 signalling from collagen protein synthesis in Dupuytren's disease

The Journal of Pathology, EarlyView.
Abstract Dupuytren's disease is a fibroproliferative disorder of the palmer fascia (PF) characterised by flexion contractures in the hand. Dupuytren's disease can be treated surgically, but disease recurrence rates are high, potentially due to continual production of matrisomal proteins.
Gabriella Cooper, Jade A Gumbs, Sahem Alkharabsheh, Katie J Lee, Alan Carter, Hannah Coleman, Niamh S O'Heneghan‐Yates, Rama Ijaz, Emma Beamish, Lisa A Menezes, Triantafillos Liloglou, Peter D Clegg, Elizabeth G. Canty‐Laird   +12 more
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

A systematic review of glucocorticoid use in type 1 diabetes: Glycaemic effects and clinical management strategies

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Glucocorticoids (GCs) are widely utilised for the treatment of inflammatory and autoimmune conditions but often precipitate significant hyperglycaemia. People with type 1 diabetes (PWT1D) may be particularly affected due to the challenges of adjusting insulin dosing, for which recommendations remain unclear.
Alexandra Katz, Aidan Shulkin, Asmaa Housni, Amélie Roy‐Fleming, Rémi Rabasa‐Lhoret, Jean‐Francois Yale, Michael A. Tsoukas, Tricia M. Peters, Anne‐Sophie Brazeau   +8 more
wiley   +1 more source

Carpal tunnel syndrome in wheelchair users

طب جانباز, 2010
Background: Compression of median nerve at carpal tunnel or carpal tunnel syndrome (CTS) is the most common entrapment neuropathy. Due to over use of hand in wheelchair users, it is possible that carpal tunnel syndrome be more prevalent in them ...
A. Chitsaz, M. Etemadifar, F. Ferdowsi
doaj  

Splinting or surgery for carpal tunnel syndrome? Design of a randomized controlled trial [ISRCTN18853827]

BMC Neurology, 2001
Background Carpal tunnel syndrome is a common disorder, which can be treated with surgery or conservative options. However, there is insufficient evidence and no consensus among physicians with regard to the preferred treatment for carpal tunnel syndrome.
de Vet Henrica CW, Kuiper Herman, Assendelft Willem JJ, Scholten Rob JPM, Gerritsen Annette AM, Bouter Lex M   +5 more
doaj   +1 more source

Unresolved conflict in workers' compensation: The impact of legal representation on workers' compensation benefits

Journal of Risk and Insurance, EarlyView.
Abstract We estimate the causal effect of attorney involvement on the indemnity benefits workers receive after their injuries. To address the fundamental challenge that claims and injuries may differ on unmeasured dimensions that affect both attorney involvement and benefits received, we propose and use two instruments.
Bogdan Savych, David Neumark
wiley   +1 more source

Customized Metal 3D Printed Total Wrist Prosthesis in the Treatment of Severely Destroyed Wrist: Design Rationale and Clinical Applications

Orthopaedic Surgery, Volume 17, Issue 5, Page 1536-1546, May 2025.
Four patients with severe wrist destruction from various causes were treated with customized 3D‐printed prostheses. In addition to the specific articular surface matching their original radiocarpal joint, two innovative proximal component designs were created to address different bone defects.
Qipei Wei, Chang Liu, Shanlin Chen, Min Liu   +3 more
wiley   +1 more source

Sickness absence from work among persons with new physician-diagnosed carpal tunnel syndrome: a population-based matched-cohort study. [PDF]

PLoS ONE, 2015
Carpal tunnel syndrome is common among employed persons. Data on sickness absence from work in relation to carpal tunnel syndrome have been usually based on self-report and derived from clinical or occupational populations. We aimed to determine sickness
Isam Atroshi, Caddie Zhou, Anna Jöud, Ingemar F Petersson, Martin Englund   +4 more
doaj   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Sensitivity and specificity of median nerve ultrasonography in diagnosis of carpal tunnel syndrome

International Journal of General Medicine, 2012
Mohammad Yazdchi1, Mohammad Kazem Tarzemani2, Haleh Mikaeili3, Hormoz Ayromlu1, Hooman Ebadi11Neuroscience Research Center, 2Department of Radiology, 3Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz ...
Yazdchi M, Tarzemani MK, Mikaeili H, Ayromlu H, Ebadi H   +4 more
doaj