Results 61 to 70 of about 361,258 (350)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Carbapenem- and colistin-resistant Enterobacterales in intensive care unit patients in Mediterranean countries, 2019

Frontiers in Microbiology
IntroductionThe colonization of patients by carbapenemase-producing Enterobacterales (CPE) has been associated with heightened mortality, especially in vulnerable individuals within intensive care units (ICUs).
Sandra Dos Santos, Seydina M. Diene, Seydina M. Diene, Seydina M. Diene, Amina Benouda, Khalid Zerouali, Doaa M. Ghaith, Rasha H. El-Mahdy, Sawsan H. M. El Tayeb, Ilhem Boutiba, Adnene Hammami, Remie Chrabieh, Ziad Daoud, Laurent Mereghetti, Patrice Francois, Nathalie Van Der Mee-Marquet, on behalf of the consortium   +16 more
doaj   +1 more source

Klebsiella pneumoniae carriage in low-income countries: antimicrobial resistance, genomic diversity and risk factors

Gut Microbes, 2020
Background: Klebsiella pneumoniae (hereafter, Kp) is a major public health threat responsible for high levels of multidrug resistant (MDR) human infections.
Bich-Tram Huynh, Virginie Passet, Andriniaina Rakotondrasoa, Thierno Diallo, Alexandra Kerleguer, Melanie Hennart, Agathe De Lauzanne, Perlinot Herindrainy, Abdoulaye Seck, Raymond Bercion, Laurence Borand, Maria Pardos de la Gandara, Elisabeth Delarocque-Astagneau, Didier Guillemot, Muriel Vray, Benoit Garin, Jean-Marc Collard, Carla Rodrigues, Sylvain Brisse   +18 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Limited asymptomatic carriage of Pneumocystis jiroveci in human immunodeficiency virus-infected patients [PDF]

, 2003
Forty-seven bronchoalveolar lavage fluid samples from 16 human immunodeficiency virus (HIV)-infected patients were used to test the latency model of Pneumocystis infection in the human host.
Ambrose, HE, Denis, CM, Lindley, AR, Miller, RF, Wakefield, AE   +4 more
core  

Prevalence and Characterization of Multi-Drug-Resistant Gram-Negative Bacilli Isolated From Lebanese Poultry: A Nationwide Study

Frontiers in Microbiology, 2018
Currently, antimicrobial resistance is one of the most prominent public health issues. In fact, there is increasing evidence that animals constitute a reservoir of antimicrobial resistance.
Iman Dandachi, Iman Dandachi, Elie S. Sokhn, Elias A. Dahdouh, Eid Azar, Bassel El-Bazzal, Jean-Marc Rolain, Ziad Daoud   +7 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Emitted vibration measurement device and method [PDF]

, 1986
This invention is directed to a method and apparatus for measuring emitted vibrational forces produced by a reaction wheel assembly due to imbalances, misalignment, bearing defects and the like.
Gisler, G. L.
core   +1 more source

Differential expression of hemoglobin receptor, HmbR, between carriage and invasive isolates of Neisseria meningitidis contributes to virulence: lessons from a clonal outbreak

Virulence, 2018
Carriage and invasion balance in the pathogenesis of Neisseria meningitidis was analyzed during a recent clonal outbreak of meningococcal B in Normandy, France, that offered the opportunity to compare six isolates undistinguable by conventional typing (B:
Julien Sevestre, Seydina M. Diene, Myriam Aouiti-Trabelsi, Ala-Eddine Deghmane, Isabelle Tournier, Patrice François, François Caron, Muhamed-Kheir Taha   +7 more
doaj   +1 more source

Infection with and carriage of Mycoplasma pneumoniae in children

Frontiers in Microbiology, 2016
Atypical pneumonia was described as a distinct and mild form of community-acquired pneumonia (CAP) already before Mycoplasma pneumoniae had been discovered and recognized as its cause. M.
Patrick M. eMeyer Sauteur, Patrick M. eMeyer Sauteur, Patrick M. eMeyer Sauteur, Wendy W. J. eUnger, David eNadal, Christoph eBerger, Cornelis eVink, Annemarie M.C. evan Rossum   +7 more
doaj   +1 more source