Results 41 to 50 of about 2,189,484 (293)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Americans' Access to Prescription Drugs Stabilizes, 2007-2010 [PDF]

open access: yes, 2011
Examines trends in the percentage of Americans reporting difficulty affording prescription drugs by insurance status, age group, income, and health status.
Ellyn Boukus, Emily R. Carrier
core  

Graphene for Antenna Applications: Opportunities and Challenges from Microwaves to THz

open access: yes, 2012
The use of graphene for antennas and other electromagnetic passives could bring significant benefit such as extreme miniaturization, monolithic integration with graphene RF nanoelectronics, efficient dynamic tuning, and even transparency and mechanical ...
Perruisseau-Carrier, Julien
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Optically induced free carrier light modulator [PDF]

open access: yes, 1969
Signal carrier laser beam is optically modulated by a second laser beam of different frequency acting on a free carrier source to which the signal carrier laser is directed.
Gruber, C. L., Richards, W. E.
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Review of standards for biodegradable plastic bags. [PDF]

open access: yes, 2015
The Single Use Carrier Bags Charges (England) Order 2015 requires retailers to charge at least 5p for each single use carrier bag, except where exempted. Under section 18 of that order, the Secretary of State must— (a) complete a review of industry
Boardman, Carl   +6 more
core  

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim   +8 more
wiley   +1 more source

Viscoelastic Characterization of Polymer-Modified Asphalt Binders of Pavement Applications

open access: yesApplied Rheology, 2003
Rutting is a primary reason of premature deterioration of asphalt highway pavements. Pavements constructed with polymer and other modifiers are showing improved performance.
Uddin Waheed
doaj   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter   +17 more
wiley   +1 more source

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