Results 171 to 180 of about 404,297 (306)

Foam as a carrier phase: A multipurpose technology for industrial applications: Dissertation

open access: yes, 2017
The applicability of foam in paper/board manufacturing processes was studied. The pulp and paper production in Finland has been forecast to decrease by up to a third from 2007 to 2020. The declining trend is mainly due to the weakening of main export markets.
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Investigation of Offset Recovery Algorithms for High-Performance Bluetooth Receivers

open access: yes, 2005
Research has shown that significant degradation in performance can occur even when operating within the limits for carrier frequency and modulation index offsets permitted by the Bluetooth standard.
Tibenderana, C   +3 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Reduced Complexity In-phase/Quadrature-phase Turbo Equalisation Using Radial Basis Functions

open access: yes, 2001
A novel reduced complexity Radial Basis Function (RBF) neural network based equaliser, referred to as the In-phase/Quadrature-phase RBF Equaliser (I/Q-RBF-EQ), is proposed. The I/Q-RBF-EQ is employed in the context of turbo equalisation (TEQ) assisted by
Yeap, B.L., Yee, M.S., Hanzo, L.
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy