Results 161 to 170 of about 1,470 (223)

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Advances in Microbial Diagnostics: Machine Learning and Nanotechnology for Zoonotic Disease Control. [PDF]

Wiley Interdiscip Rev Nanomed Nanobiotechnol
Lotfalizadeh N, Santucciu C, Chisu V, Sepahvand H, Rahdar A, Behzadmehr R, Franco OL, Moez G, Ferreira LFR.   +8 more
europepmc   +1 more source

How We Simulate Nanopores

Small Methods, EarlyView.
Nanopore technology has revolutionized single‐molecule sensing, yet it suffers from an inherent interpretive challenge. Molecular dynamics has emerged as a go‐to method for determining the relationship between the structure of translocating molecules and the nanopore current signals.
Behzad Mehrafrooz, Xavier Mleziva, Meng Xu, Melika Shekari, Christopher Maffeo, Aleksei Aksimentiev   +5 more
wiley   +1 more source

Assessing the diversity of zoonotic bacterial agents in rodents and small mammals in Iran. [PDF]

Eur J Public Health
Rezaie N, Latifian M, Ghasemi A, Mahmoudi A, Baseri N, Omidi AH, Esmaeili P, Esmaeili S, Mostafavi E.   +8 more
europepmc   +1 more source

Impact of Environmental Microparticles on Insect Olfaction

Environmental Toxicology, EarlyView.
ABSTRACT Terrestrial insects underpin key ecosystem services, including pollination, herbivory regulation, decomposition, nutrient cycling, and disease control. These functions depend on chemical communication that guides insects to food, mates, hosts, shelters, and oviposition sites while helping them avoid threats.
Steve B. S. Baleba, Danube K. N. Wandji, Yves H. Tchiechoua, Komi Mensah Agboka, Iman B. Hassaballa, Victor O. Omondi, Beatrice T. Nganso, Saliou Niassy, Souleymane Diallo, Merid N. Getahun   +9 more
wiley   +1 more source

Ticks: Biology, Habitat, Threats and Protection Methods. [PDF]

Biology (Basel)
Szalata M, Wielgus K, Danielewski M, Hnatyszyn A, Szalata M, Skrzypczak-Zielińska M, Słomski R.   +6 more
europepmc   +1 more source

Urban bats show dietary flexibility in aquatic arthropod consumption at urban and rural waterbodies

Wildlife Biology, EarlyView.
Urban waterbodies are critical for biodiversity and provide feeding grounds for insectivorous bats. Yet, how urbanisation affects bats' food choices at urban waterbodies and the role of emergent aquatic arthropods remain poorly understood. We compared the diet of three urban bat species – Vespadelus vulturnus, Chalinolobus gouldii,and Myotis macropus –
Tanja M. Straka, Melissa E. Carew, Isabel Valenzuela, Stephen R. Griffiths, Pia E. Lentini, Linda F. Lumsden, Rahul Rane, Rodney Ree van der   +7 more
wiley   +1 more source

Advances in DNA nanostructures for pathogenic microorganisms. [PDF]

Mater Today Bio
Han X, Zhang J, Pang S, Wei G, Niu J, Lu Y, Xi J.   +6 more
europepmc   +1 more source

Stem Cell-Delivered Cytosine Deaminase/5-Fluorocytosine and TRAIL Gene Therapy for Castration-Resistant Prostate Cancer: Translational Synthesis and First-in-Human Trial Concept. [PDF]

Int J Mol Sci
Kim JH, Song M, Lee K, Lee SH, Song YS.
europepmc   +1 more source

Index Insurance and Food Security Among Smallholder Farmers in Southern Mali

Journal of Agricultural Economics, EarlyView.
ABSTRACT Climate extremes increasingly threaten food security in low‐ and middle‐income countries, where vulnerable smallholder farmers often lack access to risk mitigation tools. Although index‐based insurance has been promoted as a promising adaptation measure to climate shocks, evidence on its welfare effects, especially on food security, remains ...
Anna Mader, Tim Ölkers, Oliver Mußhoff
wiley   +1 more source