Carrion's Disease: More Than a Sand Fly-Vectored Illness. [PDF]
Carrion’s disease is a biphasic illness (S1 Fig) caused by an infection of Bartonella bacilliformis, a bacterium that is transmitted through bites of certain phlebotomine sand flies in the Andean valleys of Peru and in some areas of Ecuador and southern ...
Maria J Pons +3 more
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Bartonella bacilliformis: a systematic review of the literature to guide the research agenda for elimination. [PDF]
BackgroundCarrion's disease affects small Andean communities in Peru, Colombia and Ecuador and is characterized by two distinct disease manifestations: an abrupt acute bacteraemic illness (Oroya fever) and an indolent cutaneous eruptive condition ...
Nuria Sanchez Clemente +8 more
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Update on tegumentary leishmaniasis and Carrion’s disease vectors in Peru
Among approximately 190 species of Lutzomyia in Peru, only a small number have been identified as vectors of tegumentary leishmaniasis in Western and inter-Andean valleys. These include L. peruensis, L. verrucarum, L. tejadai, L.
Victor Zorrilla +3 more
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One hundred years after the expedition by Harvard University to Peru to investigate Carrion’s disease. Lessons for science [PDF]
In 1913, around 100 years ago, the Harvard University sent an expedition to Peru, led by Richard Strong, to investigate Carrion’s disease. This paper provides a critical review of the scientific research carried out in this expedition. Richard Strong was
David Salinas-Flores
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An unidentified cluster of infection in the Peruvian Amazon region
Introduction: Bartonella bacilliformis is the etiological agent of Carrion’s disease, which is a neglected disease linked to people in low-socioeconomic populations in Andean valleys. An outbreak of B.
Angela Cornejo +7 more
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Prioritisation of potential drug targets against Bartonella bacilliformis by an integrative in-silico approach [PDF]
BACKGROUND Carrion’s disease (CD) is a neglected biphasic illness caused by Bartonella bacilliformis, a Gram-negative bacteria found in the Andean valleys.
Mariella Farfán-López +6 more
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Immunosuppressive and angiogenic cytokine profile associated with Bartonella bacilliformis infection in post-outbreak and endemic areas of Carrion's disease in Peru. [PDF]
Analysis of immune responses in Bartonella bacilliformis carriers are needed to understand acquisition of immunity to Carrion's disease and may allow identifying biomarkers associated with bacterial infection and disease phases.
Maria J Pons +8 more
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Molecular Characterization of Fluoroquinolone-Resistant Bartonella bacilliformis [PDF]
The presence of amino acid changes in GyrA, GyrB, ParC, ParE, and in a proposed chromosomal chloramphenicol acetyl transferase (CAT), as well as mutations at 23S rRNA, were established by PCR and sequencing in 38 B.
Giovanna Mendoza-Mujica +2 more
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Frequencies of Blood Group Systems MNS, Diego, and Duffy and Clinical Phases of Carrion’s Disease in Amazonas, Peru [PDF]
Carrion’s disease (CD), is a human bartonellosis, that is, endemic in the Andes of Peru, Ecuador, and Colombia. Bartonella bacilliformis, a native hemotrophic bacteria, is the causative agent of CD, and the interaction with the host could have produced ...
Oscar Acosta +5 more
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Colonization of Lutzomyia verrucarum and Lutzomyia longipalpis Sand Flies (Diptera: Psychodidae) by Bartonella bacilliformis, the Etiologic Agent of Carrión's Disease. [PDF]
Bartonella bacilliformis is a pathogenic bacterium transmitted to humans presumably by bites of phlebotomine sand flies, infection with which results in a bi-phasic syndrome termed Carrión's disease. After constructing a low-passage GFP-labeled strain of
James M Battisti +2 more
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