Results 171 to 180 of about 11,339,765 (297)

Climate warming and bumble bee declines: the need to consider sub-lethal heat, carry-over effects, and colony compensation. [PDF]

Front Physiol, 2023
White SA, Dillon ME.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Randomised control trial on the sustained carry-over effects of pulsed electromagnetic field therapy for the treatment of Achilles tendinopathy. [PDF]

Sci Rep
Ko VM, Fu SC, Yung PS, Ling SK.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Manipulating Individual State During Migration: Carry-Over Effects of Cumulative Stress on Survival. [PDF]

Ecol Evol
Grentzmann IP, Gauthier G, Angelier F, Bêty J, LeTourneux F, Legagneux P.   +5 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Carry-over effect of immunotherapy in patients with advanced hepatocellular carcinoma. [PDF]

Cancer Immunol Immunother
Chuang CH, Chen CT, Hsu CH, Shao YY.
europepmc   +1 more source

Carry-over effects and fitness trade-offs in marine life histories: The costs of complexity for adaptation. [PDF]

Evol Appl, 2023
Marshall DJ, Connallon T.
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Sex-Dependent Carry-Over Effects Between Physiological State and Reproduction in a Passerine Species. [PDF]

Ecol Evol
Szabó G, Boross N, Hegyi G, Herényi M, Jablonszky M, Kötél D, Krenhardt K, Markó G, Nagy G, Rosivall B, Szász E, Szöllősi E, Zsebők S, Török J, Laczi M.   +14 more
europepmc   +1 more source