Results 31 to 40 of about 73,054 (262)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Carry trade [PDF]

open access: yesMNB Bulletin, 2010
This study summarises the basic facts related to the investment strategy known as carry trade. Carry trade is a leveraged investment transaction limited to the foreign exchange market. Foreign investors can only realise extra return if they also assume the risk of exchange rate fluctuations. Carry trade produces high returns for years, but in turbulent
openaire   +2 more sources

Dynamic Connectedness Among Key Financial Markets and the Role of Policy Uncertainty: A Quantile-Based Approach

open access: yesRisks
This paper investigates the return spillover dynamics among carry trade, stock, foreign exchange, and commodity markets to identify their roles as net transmitters or receivers of shocks under varying market conditions.
Lumengo Bonga-Bonga
doaj   +1 more source

Macroeconomic Determinants of Carry Trade Activity [PDF]

open access: yesReview of International Economics, 2010
AbstractCarry trades—popular strategies in the foreign exchange market—are long positions in high interest rate currencies financed through funds borrowed from low interest rate currencies. It has been shown for a number of bilateral exchange rates vis‐à‐vis the US dollar that shocks to interest rate differentials foster carry trade activity and lead ...
Alessio Anzuini, Fabio Fornari
openaire   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Asymetrix Currency Turbulence with US Dollar/Japanese Yen Carry Trade: Insights into Central Bank Interventions and Exchange-Rate Dynamics [PDF]

open access: yesFinancial Markets, Institutions and Risks
This study investigates the time-varying effectiveness of central bank interventions in the USDJPY exchange rate market, focusing on their asymmetric impacts under varying market conditions.
Masaaki Yoshimori
doaj   +1 more source

Analysis of legal regulations on agricultural trade in the post-epidemic era

open access: yesActa Agriculturae Scandinavica. Section B, Soil and Plant Science, 2022
The impact of the epidemic and a series of strict prevention and control measures taken to prevent the spread of the epidemic will have a significant impact on the entire chain and various fields of agricultural production and operation.
Xia Li
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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