Results 71 to 80 of about 1,478,032 (296)

Generalized model of blockage in particulate flow limited by channel carrying capacity

, 2015
We investigate stochastic models of particles entering a channel with a random time distribution. When the number of particles present in the channel exceeds a critical value $N$, a blockage occurs and the particle flux is definitively interrupted.
Angelani, L., Barre, C., Gabrielli, A., Talbot, J., Viot, P.   +4 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Performance of Three Reanalysis Precipitation Datasets over the Qinling-Daba Mountains, Eastern Fringe of Tibetan Plateau, China

Advances in Meteorology, 2019
Evaluation of different reanalysis precipitation datasets is of great importance to understanding the hydrological processes and water resource management practice in the Qinling-Daba Mountains (QDM), located at the eastern fringe of the Tibetan Plateau.
Gefei Wang, Xiaowen Zhang, Shiqiang Zhang   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Integrated Machine Learning Approaches for Landslide Susceptibility Mapping Along the Pakistan–China Karakoram Highway

Land
The effectiveness of data-driven landslide susceptibility mapping relies on data integrity and advanced geospatial analysis; however, selecting the most suitable method and identifying key regional factors remains a challenging task.
Mohib Ullah, Haijun Qiu, Wenchao Huangfu, Dongdong Yang, Yingdong Wei, Bingzhe Tang   +5 more
doaj   +1 more source

Monitoring Status Daya Dukung Perairan Waduk Wadaslintang Bagi Budidaya Keramba Jaring Apung Monitoring of Carrying Capacity Status of Wadaslintang Reservoir on Cage Net ) [PDF]

, 2009
Carrying capacity of waters is defined by physical condition such as quantity and quality of the waters. Physical condition alteration from time to time can cause alteration of the carrying capacity status.
Piranti, A. S. (Agatha), Rahayu, D. R. (Diana), Widyastuti, E. (Endang)   +2 more
core   +3 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Optimal growth trajectories with finite carrying capacity [PDF]

, 2016
We consider the problem of finding optimal strategies that maximize the average growth rate of multiplicative stochastic processes. For a geometric Brownian motion, the problem is solved through the so-called Kelly criterion, according to which the ...
Caccioli, F, Caravelli, F, Sindoni, L, Ududec, C   +3 more
core   +2 more sources