Results 141 to 150 of about 921,908 (302)

Factors associated with carrying out activities to stimulate child development in the family context. [PDF]

J Pediatr (Rio J)
Teixeira JH, Teixeira JA, Venancio SI, Linhares MBM, Lerner R, Menezes-Filho NA, Mello DF, CPAPI - The Brazilian Center for Early Child Development – Centro Brasileiro de Pesquisa Aplicado à Primeira Infância.   +7 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Interplanner variability in carrying out three-dimensional conformal radiation therapy for non-small-cell lung cancer

, 2008
Interplanner variability in carrying out three-dimensional conformal radiation therapy for non-small-cell lung ...
C Laferlita (13710724), M Schneider-Kolsky (13710727), M Mac (13710733), John Reynolds (13054194), S Everitt (13421283), T Kron (9098777), N Fimmell (13710721), D Ball (9850265), R Budd (13710730)   +8 more
core  

A Guide to Carrying Out a Phylogenomic Target Sequence Capture Project. [PDF]

Front Genet, 2019
Andermann T, Torres Jiménez MF, Matos-Maraví P, Batista R, Blanco-Pastor JL, Gustafsson ALS, Kistler L, Liberal IM, Oxelman B, Bacon CD, Antonelli A.   +10 more
europepmc   +1 more source

[Carrying out digital work situation analyses for mobile flexible work to ascertain the consequences of mental stress]. [PDF]

Zentralbl Arbeitsmed Arbeitsschutz Ergon, 2022
Bölsch-Peterka R, Krowicki M, Schmidtke A, Böckelmann I.   +3 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Ten simple rules for successfully carrying out funded research projects. [PDF]

PLoS Comput Biol
Forero DA, Curioso WH, Wang W.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Fonseca's Questionnaire Is a Useful Tool for Carrying Out the Initial Evaluation of Temporomandibular Disorders in Dental Students. [PDF]

Clin Pract
Mitro V, Caso AR, Sacchi F, Gilli M, Lombardo G, Monarchi G, Pagano S, Tullio A.   +7 more
europepmc   +1 more source

Exploring the views of stakeholders about the feasibility of carrying out a randomised controlled trial of Individual Placement and Support for people unemployed with chronic pain based in primary care (the InSTEP study). [PDF]

Pilot Feasibility Stud, 2020
Holmes MM, Stanescu SC, Linaker C, Price C, Maguire N, Fraser S, Cooper C, Walker-Bone K.   +7 more
europepmc   +1 more source