Results 91 to 100 of about 27,133 (260)

Repeated Measurement Designs of Five Periods: Estimating the Parameter of Carryover Effects

open access: yesStats
This study investigates the derivation of optimal repeated measurement designs of two treatments, five periods, and n experimental units for carryover effects. The optimal designs are determined for cases where n = 0, 1 (mod 2).
Miltiadis S. Chalikias
doaj   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

open access: yesDrug Testing and Analysis, EarlyView.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza   +7 more
wiley   +1 more source

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

open access: yesDrug Testing and Analysis, EarlyView.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda   +9 more
wiley   +1 more source

Simultaneous Detection of Steroid Esters and Multi‐Class Substances in Dried Blood Spots by LC‐HRMS/MS From a Single Spot for Human Doping Control

open access: yesDrug Testing and Analysis, EarlyView.
A validated LC‐HRMS/MS method enabled, for the first time, the comprehensive detection of steroid esters and multi‐class menu substances from a single dried blood spot. Following extraction, the resulting extract is split into two aliquots, reducing sample consumption and simplifying the analytical workflow.
Panagiotis Sakellariou   +4 more
wiley   +1 more source

A shining starlet: Nematostella vectensis as a model for developmental, regenerative, and comparative biology

open access: yesDevelopmental Dynamics, EarlyView.
Abstract The sea anemone, Nematostella vectensis, has been used as a model organism in developmental biology studies for many years. This estuarine species has the notable capacity to regenerate its full body plan from small pieces throughout life. Nematostella have been described as having a great degree of cellular plasticity.
Patrick A. Lewis   +3 more
wiley   +1 more source

A spreadsheet program for making a balanced Latin Square design Hoja de cálculo para balancear diseños experimentales del tipo Cuadrado Latino Planilha eletrônica para balancear delineamentos experimentais de tipo Quadrado Latino

open access: yesRevista Colombiana de Ciencias Pecuarias, 2009
Latin square designs are often employed in animal experiments to minimize the number of animals required to detect statistical differences. Generally, potential carryover effects are not balanced out by randomization.
Beob G Kim, Hans H Stein
doaj  

Revealing the Assembly Design of a BYD 46120 LFP Cylindrical Cell Through Systematic Teardown Analysis

open access: yesEcoEnergy, EarlyView.
The internal assembly design of a commercial BYD 46120 LFP cylindrical lithium‐ion battery was revealed through systematic mechanical teardown and multi‐scale analysis. Key features, including a tabless electrode architecture, engineered current‐collecting disks, separator‐core mandrel design, and electrolyte composition, are reconstructed to provide ...
Rae Hyeong Lee   +6 more
wiley   +1 more source

phenological carryover effect (data)

open access: yes
phenological data used in the ...
openaire   +1 more source

Low‐intensity focused ultrasound neuromodulation for drug‐resistant epilepsy: A randomized, sham‐controlled crossover trial

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the safety, feasibility, and efficacy of low‐intensity focused ultrasound (LIFU) as a noninvasive neuromodulation technique in patients with drug‐resistant epilepsy (DRE). Methods In this pilot, single‐blind, randomized sham‐controlled crossover trial, 12 patients with DRE underwent both LIFU and
Chien‐Chen Chou   +8 more
wiley   +1 more source

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