Results 141 to 150 of about 387,772 (298)

A Degradable Bioinspired Flier with Aerogel‐Based Colorimetric Sensors for Environmental Monitoring

Advanced Science, EarlyView.
Biodegradable fliers are developed inspired by Tipuana tipu samaras, integrating cellulose nanocrystal aerogel (CNCa) sensors loaded with natural dyes for pH and ammonia detection. The lightweight, degradable fliers mimic natural morphology and aerodynamics, offering an eco‐friendly, scalable solution for in situ environmental monitoring after passive ...
Gianpaolo Gallo, Ruowen Tu, Carlo Filippeschi, Stefano Mariani, Barbara Mazzolai   +4 more
wiley   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Outcomes for CART as 2L vs 3L vs 4L or beyond in aggressive B-cell lymphoma: real-world evidence from the ABC Consortium. [PDF]

Blood Adv
Wang JS, Ellsworth BL, Melody M, Epperla N, Stephens D, Romancik J, Cortese M, Bhansali R, Moyo TK, Kenkre V, Ollila T, Hess B, Fitzgerald L, Shouse G, Matasar M, Herr MM, Davis J, Jesme C, Pelcovits AR, Moreira J, Lin AY, Ma S, Winter JN, Danilov AV, Shah NN, Barta SK, Cohen JB, Gordon LI, Grover N, Karmali R.   +29 more
europepmc   +1 more source

A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury

Advanced Science, EarlyView.
A macrophage–platelet conjugation system (M‐P‐NPs@PPARγ) targets injure tissue to co‐deliver platelet mitochondria and PPARγ‐encoding NPs. This strategy boosts the macrophage energy supply and restores lipid homeostasis, leading to synergistically enhanced efferocytosis and tissue repair Abstract Mitochondrial dysfunction occurs in macrophages with ...
Haoli Wang, Hao Hu, Yijun Li, Lintao Hu, Chenhui Gu, Yiwei Zhu, Jing Huang, Na Li, Shuqi Jiang, Shouyan Zu, Jiachen Xu, Yining Wang, Ke Yang, Pengfei Chen, Liqing Shangguan, Yongcheng Wang, Shunwu Fan, Xianfeng Lin, Qingqing Wang   +18 more
wiley   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

The Pleiotropic Roles of Cytokines in Chimeric Antigen Receptor T-cell Therapy. [PDF]

Cancer Immunol Res
Stewart CM, Siegler EL, Kenderian SS.
europepmc   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

Advanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen, Ioannis Ziogas, Shirina Alsaedi, Mouza Alshehhi, Shahd Almheiri, Adil Rehman, Khulood Al Shehhi, Hani Saleh, Ahsan Khandoker, Charalampos Pitsalidis, Antoun Khawaja, Anna‐Maria Pappa   +11 more
wiley   +1 more source

Clinical Outcomes and Healthcare Costs of CART Versus Paracentesis for Malignant Ascites: A Nationwide Retrospective Cohort Study in Japan. [PDF]

Cancer Med
Hashimoto Y, Inoue N, Imai S.
europepmc   +1 more source

Miniature Robotic Swimmer with Precise 2D Motion Control via Acoustic Vortex‐Induced Propulsion

Advanced Science, EarlyView.
In this work, a miniature robotic swimmer achieves precise 2D motion using sound waves with customized 3D‐printed lenses. Localized acoustic vortices drive both translation and rotation of the swimmer without mechanical parts. This contactless approach offers a novel route to controlled micro‐scale movement, with promising applications in biomedical ...
Chadi Ellouzi, Nicholas Andrianto, Glen Vosgerichian, Farhood Aghdasi, Joshua Lloyd, Ali Zabihi, Chen Shen   +6 more
wiley   +1 more source