Dual inhibition of carbonic anhydrases VA and VII by silychristin and isosilybin A from Silybum marianum: A potential antiobesity strategy. [PDF]
Safer treatments for obesity are urgently needed, as many drugs were withdrawn due to their severe side effects. Targeting human carbonic anhydrase V (hCA V), the key to glucose homeostasis, shows promise. Silymarin from milk thistle is highlighted as a dual inhibitor of hCA V and VII, addressing metabolic dysregulation and oxidative stress, and ...
Citriniti EL +7 more
europepmc +2 more sources
Discover the Power of Lithospermic Acid as Human Carbonic Anhydrase VA and Pancreatic Lipase Inhibitor Through In Silico and In Vitro Studies. [PDF]
Aiming at safe obesity drugs, Salvia miltiorrhiza was explored, and lithospermic acid was identified as a dual inhibitor of pancreatic lipase and human carbonic anhydrase VA. In silico and experimental analyses revealed stable binding interactions and good inhibitory effects.
Citriniti EL +10 more
europepmc +2 more sources
The Last of England: Banal Nationalism and Communities of Loss in British Pub Closure Media Narratives. [PDF]
ABSTRACT While pubs have long been celebrated as a quintessential part of British culture, the ongoing and increasingly rapid closure of British pubs has raised concerns about the impacts of their loss on the wider cultural life and identity of the nation.
Deakin R, Thurnell-Read T.
europepmc +2 more sources
The Legacy Of Magna Carta And The Rule Of Law In The Republic Of Macedonia
The rules as we know today in modern societies have their base in the Magna Carta from 1215. In that time people declared that the rights of the king and nobles must be limited and that was the first step toward as we know today “democracy”.
Stefanovska Vesna
doaj +1 more source
Right To Property: From Magna Carta To The European Convention On Human Rights
Property rights are integral part of the freedom and prosperity of every person, although their centrality has often been misprized and their provenance was doubted.
Ristik Jelena
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La Constitución de la República de Cuba promulgada el 10 de abril de 2019 incorpora el elemento cultural como uno de sus fundamentos. Con ello, la nueva Carta Magna podría ser considerada una Constitución cultural.
Eduardo Antonio Sardá Lloga +1 more
doaj +1 more source
The Magna Carta Manifesto. Liberties and Commons for All (Berkeley: University of California Press, 2008)
Fernando Suárez Sánchez
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La Constitución de la República de Texas de 1836
El ensayo reflexiona sobre la naturaleza, antecedentes y características de la Constitución de la República de Texas de 1836. Esta Constitución fue copiada de la de Estados Unidos e implicó el interregno jurídico previo a la incorporación de Texas a ...
Jaime Cárdenas Gracia
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Lewis, Henry III: The Son of Magna Carta (Amberley Books, 2016)
Review of Matthew Lewis, Henry III: The Son of Magna Carta (Stroud: Amberley Books, 2016).
Stephen Donnachie
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The Influence Of Magna Carta Libertatum In The Development Of The Principle Of Rule Of Law
The concept of Rule of Law is the cornerstone of the proper functioning of the judicial system in any modern democratic society. It is a basic concept of defined rights and liberties to all persons, which offers protection from arbitrary prosecution and ...
Bozhinovski Andrej
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