Results 111 to 120 of about 2,775,539 (295)

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source

FUCA: a Frame to Prevent the Generation of Useless results in the Dataflows Based on Cartesian Product for Convolutional Neural Network Accelerators [PDF]

International Journal of Information and Communication Technology Research
One of the most important issues in the design of CNN accelerators pertains to the accelerator's ability to effectively leverage the available opportunities in the type and processing of input data, and the task of achieving this objective mostly lies ...
Babak NarimanJahan, Ahmad Khademzadeh, Akram Reza   +2 more
doaj  

Power domination of the cartesian product of graphs

AKCE International Journal of Graphs and Combinatorics, 2016
In this paper, we first give a brief survey on the power domination of the Cartesian product of graphs. Then we conjecture a Vizing-like inequality for the power domination problem, and prove that the inequality holds when at least one of the two graphs ...
K.M. Koh, K.W. Soh
doaj   +1 more source

On the cartesian product of intuitionistic fuzzy sets

, 2003
Cartesian products of intuitionistic fuzzy sets have been defined using the min-max and the product-probabilistic sum operations. In this paper we introduce and analyse the properties of a generalized cartesian product of intuitionistic fuzzy sets using ...
Kerre, Etienne, Deschrijver, Glad
core  

A combinatorial lemma on the cartesian product of finite sets

, 1993
A sufficient condition for the cartesian product of a finite family of equipotent finite sets to have elements without repetitions is given, and some application is ...
Girardi, A., Bartocci, U.
core   +1 more source

Discrete 2D Material Programming for 3D Shaping and Morphogenesis‐Inspired 4D Bioprinting

Advanced Science, EarlyView.
Cell‐compatible discrete 2D material programming enables 2‐to‐3D shape transformation and morphogenesis‐inspired 4D bioprinting. By patterning cell‐supportive microdomains within a responsive hydrogel, the approach programs in‐plane growth to encode target metrics.
Fereshteh Family, Aneela Davuluri, Athulya Martin, Kyungsuk Yum   +3 more
wiley   +1 more source

On the cartesian product of intuitionistic fuzzy sets.

, 2001
Cartesian products of intuitionistic fuzzy sets have been defined using the min-max and the product-probabilistic sum operations. In this paper we introduce and analyse the properties of a generalized cartesian product of intuitionistic fuzzy sets using
Kerre, Etienne, Deschrijver, Glad
core  

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Sequential Patterning of Photoresponsive Hydrogels Directs Crypt Fission and Reveals the Role of Epithelial Curvature on Fission Symmetry

Advanced Science, EarlyView.
Deterministic crypt fission is achieved in intestinal organoids using photopatternable hydrogels with spatiotemporal control. Daughter‐crypt symmetry is shown to depend on parent‐crypt geometry and epithelial curvature, while myosin‐dependent mechanosensing links tissue shape to regenerative outcomes.
Delaney L. McNally, Kaustav Bera, Nolan R. Petrich, Alex Khang, Marilyne Coulombe, David Castillo‐Azofeifa, Ophir D. Klein, Peter J. Dempsey, Kristi S. Anseth   +8 more
wiley   +1 more source

DyProL: Dynamic Ensemble Representation Learning for Protein–Nucleic Acid Binding Site Prediction

Advanced Science, EarlyView.
Protein function is represented as a dynamic conformational ensemble rather than a single static structure. A multi‐conformation geometric attention framework aligns, clusters, and learns representative states to capture residue‐ and ensemble‐level signals. Integrating structural dynamics improves interpretable protein‐NA binding prediction and reveals
Pengpai Li, Yiman Liu, Liya Liang, Rongming Liu   +3 more
wiley   +1 more source