MAVISp: A modular structure‐based framework for protein variant effects
Abstract The role of genomic variants in disease has expanded significantly with the advent of advanced sequencing techniques. The rapid increase in identified genomic variants has led to many variants being classified as Variants of Uncertain Significance or as having conflicting evidence, posing challenges for their interpretation and ...
Matteo Arnaudi +32 more
wiley +1 more source
BCMA-directed mRNA CAR-T cell therapy for myasthenia gravis: exploratory biomarker analysis of a placebo-controlled phase 2b trial. [PDF]
Fedak RR +28 more
europepmc +1 more source
CONCERT: A Modular Reconfigurable Robot for Construction
ABSTRACT This paper presents CONCERT, a fully reconfigurable modular collaborative robot (cobot) for multiple on‐site operations in a construction site. CONCERT has been designed to support human activities in construction sites by leveraging two main characteristics: high‐power density motors and modularity. In this way, the robot is able to perform a
Luca Rossini +18 more
wiley +1 more source
Network design for bypass roads using interval valued fuzzy outerplanar graphs. [PDF]
Jaisankar D +3 more
europepmc +1 more source
Vector Field‐Based Collision‐Free Navigation in Tunnel‐Like Environments
ABSTRACT Tunnel‐like environments, renowned for their vast scale, confined spaces, and limited visibility, present significant challenges for autonomous robot navigation. This study addresses the critical issue of guiding robots through such environments while ensuring collision‐free navigation and maintaining a specified safety margin from both tunnel
Bao Jianjun +5 more
wiley +1 more source
On the optimal layout of (K<sub>p</sub> - C<sub>p</sub>)<sup>n</sup> into grid and certain structures. [PDF]
Vincy GC, Micheal DR.
europepmc +1 more source
Three‐dimensional geometric morphometric analysis is a shape analysis method used to explain sexual dimorphism. In this context, a total of 13 anatomical landmarks were defined and analysed in the study, resulting in sex‐related shape variations. The study identified sex‐related morphological differences in the sella turcica structures of Romanov sheep
İhsan Berat Kiliçli +7 more
wiley +1 more source
Exploring quantum annealing for coarse-grained protein folding. [PDF]
Scheiber T, Heller M, Giebel A.
europepmc +1 more source
Evaluating Approximations of River Channel Shape Using a National Cross‐Section Database
Abstract Many hydrologic applications require basic information on the size and shape of river channels, but measuring cross section (XS) geometry in the field or via remote sensing can be costly and often provides only partial coverage. Given these challenges, we capitalized upon an existing data set of 46,971 XS from gaging stations to evaluate ...
C. J. Legleiter, P. J. Kinzel
wiley +1 more source
Advances and opportunities for computational interrogation of plant proteins
SUMMARY Plants exhibit remarkable biochemical and physiological diversity, and are capable of adapting to a wide range of environmental conditions and stresses. This complexity makes them essential systems for understanding how life responds to a changing climate.
Sarah M. Bohling +2 more
wiley +1 more source

