Results 151 to 160 of about 91,123 (253)

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

Prothrombinase processivity is conferred by substrate allostery. [PDF]

EMBO J
Üstok FI, Faille A, Warren AJ, Huntington JA.   +3 more
europepmc   +1 more source

Bio‐guided fractionation of (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid from Abelmoschus sagittifolius root as a potent α‐glucosidase inhibitor: An integrated in vitro and in silico study

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Abelmoschus sagittifolius stands out as a valuable medicinal source for developing functional food targeting type 2 diabetes. This study investigated the α‐glucosidase inhibitory potential of an active fraction obtained from A. sagittifolius roots (ASR), enriched in (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid (OA), using both enzyme ...
Nguyen Phuong Mai, Nguyen Van Quan, Nguyen Dang Duc, Tran Dang Xuan   +3 more
wiley   +1 more source

Publisher Correction: Elucidating the relationship between affinity and potency in the performance of therapeutic IgE. [PDF]

Sci Rep
Marano F, McKenzie C, Birtley JR, Hussain SA, Macleod O, Goodacre A, Wu S, Amin OE, Faulkner N, Devlin J, Regan L, Soni K, Johnson RM, Pye VE, Wilson T, Hardaker E, FitzGerald K.   +16 more
europepmc   +1 more source

Liking Without Endorsing: Consumer Dilemmas in Responses to AI‐Generated Music

Psychology &Marketing, EarlyView.
ABSTRACT Despite a growing literature documenting consumer aversion to AI‐generated creative output, AI‐generated music has achieved notable success in the marketplace, with some songs achieving chart placements and attracting millions of streams.
Andrew B. Edelblum, Joshua Poe
wiley   +1 more source

Identification of the first peptide inhibitor of UBE2C enzymatic activity: insights from metadynamics-guided folding and binding studies. [PDF]

J Enzyme Inhib Med Chem
Pirone L, Fiorillo B, Del Gatto A, Russo R, Guarracino A, Cassiano C, Zaccaro L, Moraca F, Pedone E, Catalanotti B.   +9 more
europepmc   +1 more source

Cartoon [PDF]

Ultrasound in Obstetrics & Gynecology, 2008
openaire   +1 more source

From Real to Artificial: How Profile Image Realism Shapes Warmth, Competence, and Trade Outcomes in Swapping Platforms

Psychology &Marketing, EarlyView.
ABSTRACT This research investigates how value transparency and profile image realism jointly shape consumers' perceptions and trade behavior in Consumer‐to‐Consumer (C2C) swapping platforms. Across three studies, we examine whether realistic profile images enhance perceived warmth and competence, thereby fostering trade intentions under different ...
Sarah (Sa'arah) Alhouti, Louvins Pierre, Xiexin (Leah) Liu   +2 more
wiley   +1 more source

Magnesium as a conformational gatekeeper of KRAS: Structural dynamics and therapeutic implications. [PDF]

Protein Sci
Srinivasu BY, Damerla TS, Stec A, Zhou Z, Engen JR, Westover KD, Wales TE.   +6 more
europepmc   +1 more source

Designing Thermally Stable DNA Hydrogels via Entropically‐Driven Acridine Intercalation

Macromolecular Rapid Communications, EarlyView.
Environmental variables are shown to systematically tune the network dynamics of entropy‐driven, acridine‐based DNA‐intercalating supramolecular hydrogels. Adjusting the buffer composition, ionic identity, and salt concentration impacts electrostatic screening and counterion release of the DNA backbone, offering a powerful handle to tune elasticity and
Shaina M. Hughes, Amy M. DiVito, Patrick F. Strobel, Pearson J. J. Franz, Matthew E. Currier, Nathan J. Oldenhuis   +5 more
wiley   +1 more source