Results 181 to 190 of about 337,591 (267)

Fluorinated Amphiphilic Dendrimer to Improve PET Imaging of Cancer

Small, EarlyView.
Fluorination of a self‐assembling dendrimer nanosystem reduced liver retention, accelerated renal clearance and improved biodistribution, ultimately enhancing tumor uptake and enabling more sensitive tumor detection by positron emission tomography (PET).
Béatrice Louis, Tom Roussel, Twiany Cruz‐Dubois, Ling Ding, Zhenbin Lyu, Erik Laurini, Jessica Ou, Laure Balasse, Adrien Chabert, Vincent Nail, Ahlem Bouhlel, Françoise Dignat‐George, Florence Gattacceca, Sabrina Pricl, Benjamin Guillet, Ling Peng, Philippe Garrigue   +16 more
wiley   +1 more source

Molecular basis for occlusion of the jeilongvirus receptor-binding site by the elongated C-terminus. [PDF]

mBio
Stelfox AJ, Javorsky A, Stass R, Sutton G, El Omari K, Bowden TA.   +5 more
europepmc   +1 more source

Guiding the Formation of Surface‐Confined 2D Metal–Organic Coordination Networks by Variation of Constituent Landing Energy in Electrospray Deposition of an Iron(II) Grid Complex

Small Methods, EarlyView.
Electrospray ion beam deposition (ES‐IBD) of an Fe(II) [2 × 2] grid complex onto Ag(111) reveals landing energy‐dependent fragmentation and self‐assembly. At higher landing energies, novel coordination networks emerge. This study highlights the unique potential of ES‐IBD in creating diverse metal–organic architectures on surfaces.
Dennis Meier, Benedikt Schoof, Andreas Walz, Nithin Suryadevara, Annette Huettig, Hartmut Schlichting, Joachim Reichert, Mario Ruben, Anthoula C. Papageorgiou, Johannes V. Barth   +9 more
wiley   +1 more source

Structural mechanisms of pump assembly and drug transport in the AcrAB-TolC efflux system. [PDF]

Elife
Ge X, Gu Z, Wang J.
europepmc   +1 more source

Rational Design and Development of Organic Afterglow Nanoparticles for Image‐Guided Interventions

Small Methods, EarlyView.
This review outlines the rational design, synthesis, and standardized characterization of organic afterglow nanoparticles for biomedical imaging and therapy. Mechanistic insights into chemically initiated electron exchange luminescence and reactive oxygen species‐mediated processes are connected to molecular engineering and nanoparticle fabrication ...
Asma Harun, Isabella Vasquez, Hannah Bowman, Robert Posey, Zhongkui Hong, Joshua Tropp, Indrajit Srivastava   +6 more
wiley   +1 more source

Functions of prolyl hydroxylation in elastin. [PDF]

J Biol Chem
Yang C, Schmelzer CEH, Tarakanova A.
europepmc   +1 more source

Universal Barriers and Facilitators to Systemic Hepatitis C Care: A Systems‐Informed Qualitative Process Evaluation

Systems Research and Behavioral Science, EarlyView.
ABSTRACT Scaling up hepatitis C virus (HCV) testing and treatment for people who inject drugs (PWID) is essential to achieve HCV elimination. We report a retrospective systems‐informed qualitative process evaluation of HCV care across multiple community‐based settings in a region in Scotland, UK.
Gabriele Vojt, Lawrie Elliott, Hannah E. Family, Sharon J. Hutchinson, Matthew Hickman, John F. Dillon, Paul Flowers   +6 more
wiley   +1 more source

The uncanny valley effect and immune activation in virtual reality. [PDF]

Sci Rep
Diekhof EK, Kastner S, Deinert D, Foerster M, Steinicke F.   +4 more
europepmc   +1 more source

Designing Tailored Molecular Cavities Using Calix[5]arenes as Building Blocks

The Chemical Record, EarlyView.
This account focuses on the shape and dimensions of cavities formed by precisely designed molecular frameworks. It highlights our efforts to construct synthetically tailored cavities based on calix[5]arenes. This study examines the shapes and dimensions of cavities defined by well‐designed molecular structures.
Takehiro Hirao, Takeharu Haino
wiley   +1 more source

Scaffolds with optimized quaternary symmetry for de novo cryoEM structure determination of small RNAs. [PDF]

Nat Methods
Jones CP, Ferré-D'Amaré AR.
europepmc   +1 more source