Results 181 to 190 of about 91,123 (253)

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

Dopamine D2 and GABA(A) Receptors Differentially Regulate Ethanol-Induced Aversion and Reward Through Corticolimbic Circuits. [PDF]

Int J Mol Sci
Wu CE, Lin YC, Gao ZY, Kozłowska A, Cheng CN, Wu CW, Huang ACW.   +6 more
europepmc   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Plant UBX domain-containing proteins use distinct strategies to stably engage the unfoldase CDC48A. [PDF]

Plant Cell Physiol
Zhang J, Wang J, Sandholu A, Shahul Hameed UF, Arold ST.   +4 more
europepmc   +1 more source

Functional Repurposing of Magnetic Nanoparticle‐Assisted Hyperthermia for Immune Cell Labelling and Tracking

Small Methods, EarlyView.
We propose mild‐MHT protocol for the quick internalization of magnetic nanoparticles (MNPs) by immune cells. The heat induced by MNPs under alternating magnetic field stimulate MNPs diffusion and cell membrane invagination, accelerating the cellular internalization of MNPs. ABSTRACT Immune cell therapies show promise in hematologic malignancies and are
Giulia E. P. Nucci, Chiara Vitale, Alessandro di Girolamo, Niccolò Silvestri, Stefano Persano, Lorenci Gjurgjaj, Cristina Bottino, Roberta Castriconi, Teresa Pellegrino   +8 more
wiley   +1 more source

Breaching the Blood-Brain Interface: Vasoactive Neurons Contact Capillary Vessels of the Brain Clock in the Suprachiasmatic Nucleus. [PDF]

eNeuro
Yao Y, Cannava I, Tazebay R, Samuels S, Silverstein E, Silver R.   +5 more
europepmc   +1 more source

Universal Barriers and Facilitators to Systemic Hepatitis C Care: A Systems‐Informed Qualitative Process Evaluation

Systems Research and Behavioral Science, EarlyView.
ABSTRACT Scaling up hepatitis C virus (HCV) testing and treatment for people who inject drugs (PWID) is essential to achieve HCV elimination. We report a retrospective systems‐informed qualitative process evaluation of HCV care across multiple community‐based settings in a region in Scotland, UK.
Gabriele Vojt, Lawrie Elliott, Hannah E. Family, Sharon J. Hutchinson, Matthew Hickman, John F. Dillon, Paul Flowers   +6 more
wiley   +1 more source

Structural Basis of Lipopolysaccharide O-Antigen Chain Length Modality. [PDF]

Research (Wash D C)
Wiseman B, Widmalm G, Högbom M.
europepmc   +1 more source

“All Native Speakers” at Singapore's ESL Schools: Implications for TESOL Communities in the Pursuit of Diversity‐Based Professionalism

TESOL Quarterly, EarlyView.
Abstract This study explores an understudied question of who teaches English in the Singaporean English language teaching (ELT) industry. Study 1 analyzed the website contents of ESL schools, and Study 2 conducted questionnaire surveys and interviews with three schools.
Yoko Kobayashi
wiley   +1 more source

The Hidden Hallyu Emerged: Exploring the Key Motives of Reading Adapted K‐Webtoons of South Korea

Thunderbird International Business Review, EarlyView.
ABSTRACT This study aims to investigate why global fans read Korean webtoons (K‐webtoons) and how their motivations vary across different genres. Previous studies have approached the Korean Wave (Hallyu) from a national perspective, emphasizing its influence and primarily discussing K‐pop and K‐drama.
Hoseok Gwak, Ga‐rog Han, Taehyung Kim, Minseok Kim   +3 more
wiley   +1 more source