Results 121 to 130 of about 14,223,498 (240)

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu   +5 more
wiley   +1 more source

Digital Handwriting Reveals Motor Impairment, Dopaminergic Response, and Progression in Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Digital handwriting distinguishes PD patients from healthy controls but is rarely assessed quantitatively. Objectives To evaluate digital handwriting as an objective tool to assess motor impairment, dopaminergic response, and progression in PD.
Lola Díaz‐Feliz   +7 more
wiley   +1 more source

AI‐Driven Synthesis in Medicinal Chemistry: Integrating Large Language Models, Robotic Automation, and Sustainability Metrics to Accelerate Drug Discovery

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Artificial intelligence (AI) is transforming synthetic chemistry from task‐specific predictors into integrated platforms that unify retrosynthesis, reaction optimization, and closed‐loop robotic automation. This review highlights how AI‐assisted planning and robotic execution shorten cycle times, reduce step counts, and improve route ...
Amit Gangwal, Antonio Lavecchia
wiley   +1 more source

Image‐Based Diagnosis of Oral Lesions: Performance of a Vision‐Language Model versus Human Clinicians

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the real‐world diagnostic performance of a multimodal large language model (LLM) for image‐based assessment of oral mucosal lesions compared with clinicians of varying expertise. Study Design Prospective international multicenter diagnostic accuracy study.
Luigi A. Vaira   +32 more
wiley   +1 more source

Remote Sensing Estimation of Vegetation NPP in Shaanxi Province Based on Improved CASA Model

open access: yesShuitu baochi yanjiu
[Objective] The aims of this study are to investigate the production status of vegetation communities in Shaanxi Province terrestrial ecosystems, to analyze the changes in spatial and temporal patterns of vegetation NPP and the factors affecting them ...
Zhao Xuerui   +3 more
doaj  

Clarifying Public Policy for Stronger Public Administration in Development

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT Public policy is ubiquitous, yet its meaning is often unclear. This ambiguity is not just conceptual. Because policy work is a large part of what public administrations do, how we define policy shapes how we structure and organize our administrative mechanisms.
Matt Andrews
wiley   +1 more source

Valencia : órgano de la "Casa Valencia".: I - Nº. 1

open access: yes, 1928
Microfilme.
Casa de Valencia (Barcelona)
core  

Caring with forests: Human and more‐than‐human care in forest occupations in Germany

open access: yesPeople and Nature, EarlyView.
Abstract Drawing on ongoing ethnographic and participatory action research within forest occupations in Germany, this paper develops the concept of ‘caring with forests’ to theorise the mutual, multidimensional relationships of care that emerge between humans and more‐than‐human beings in environmental protest settings.
Sebastian Garbe
wiley   +1 more source

A walk in the park—Identifying healthy greenspaces using scents

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
As urbanisation accelerates globally, access to nature is increasingly recognised as vital for public health and wellbeing. We captured and analysed plant‐emitted airborne ‘scent signatures’ across Oxford's urban greenspaces to assess their potential health relevance.
William T. Kay   +6 more
wiley   +1 more source

Genomic insights into the local adaptation of spontaneous olive trees in the Mediterranean Basin highlight the need for conservation planning in the face of global change

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
The Mediterranean Basin, a major biodiversity hotspot, is highly vulnerable to climate and global changes. Wild olive trees form an essential part of this landscape and hold strong ecological, cultural and socio‐economic significance. By examining how these trees responded to past climatic conditions, this study shows adaptation of olive trees to local
Lison Zunino   +10 more
wiley   +1 more source

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