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Enzymatic Cascade Reaction in Simple-Coacervates
The design of enzymatic droplet-sized reactors constitutes an important challenge with many potential applications such as medical diagnostics, water purification, bioengineering, or food industry. Coacervates, which are all-aqueous droplets, afford a simple model for the investigation of enzymatic cascade reaction since the reactions occur in all ...
Laurent Bouffier +2 more
exaly +6 more sources
Kinetic Insights Into ϵ-Caprolactone Synthesis: Improvement of an Enzymatic Cascade Reaction
ABSTRACTA computational approach for the simulation and prediction of a linear three‐step enzymatic cascade for the synthesis of ϵ‐caprolactone (ECL) coupling an alcohol dehydrogenase (ADH), a cyclohexanone monooxygenase (CHMO), and a lipase for the subsequent hydrolysis of ECL to 6‐hydroxyhexanoic acid (6‐HHA).
Selin Kara +2 more
exaly +4 more sources
Enzymatic Cascade Reactions in Biosynthesis [PDF]
AbstractEnzyme‐mediated cascade reactions are widespread in biosynthesis. To facilitate comparison with the mechanistic categorizations of cascade reactions by synthetic chemists and delineate the common underlying chemistry, we discuss four types of enzymatic cascade reactions: those involving nucleophilic, electrophilic, pericyclic, and radical ...
Christopher T. Walsh, Bradley S. Moore
exaly +3 more sources
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Multi-Enzymatic Cascade Reactions: Overview and Perspectives
Advanced Synthesis and Catalysis, 2011AbstractMulti‐enzymatic cascade reactions, i.e., the combination of several enzymatic transformations in concurrent one‐pot processes, offer considerable advantages: the demand of time, costs and chemicals for product recovery may be reduced, reversible reactions can be driven to completion and the concentration of harmful or unstable compounds can be ...
Joerg H. Schrittwieser
exaly +2 more sources
Enzymatic Cascade Reactions for the Efficient Synthesis of Natural Products
Tetrahedron, 2022Dong-Shan Wu, Xiaoguang Lei
exaly +2 more sources
Electrophilic and nucleophilic enzymatic cascade reactions in biosynthesis
Natural Product Reports, 2012The biosynthesis of cyclic terpenoids and polyethers involves enzyme-initiated cascade reactions for ring formation. While the former are obtained by electrophilic cascades through carbenium ions as intermediates, cyclic polyethers are formed by nucleophilic cascade reactions of (poly)epoxide precursors.
Barbara T, Ueberbacher +2 more
openaire +2 more sources
Cascade enzymatic reactions for efficient carbon sequestration
Bioresource Technology, 2015Thermochemical processes developed for carbon capture and storage (CCS) offer high carbon capture capacities, but are generally hampered by low energy efficiency. Reversible cascade enzyme reactions are examined in this work for energy-efficient carbon sequestration.
Shunxiang, Xia +5 more
openaire +2 more sources
Chemical Communications, 2021
A spatially segregative coacervate-in-proteinosome hybrid microcompartment is constructed with an enhanced cascade enzymatic reaction, providing a step towards the development of artificial eukaryotic cell like microcompartments.
Junbo Li +5 more
openaire +2 more sources
A spatially segregative coacervate-in-proteinosome hybrid microcompartment is constructed with an enhanced cascade enzymatic reaction, providing a step towards the development of artificial eukaryotic cell like microcompartments.
Junbo Li +5 more
openaire +2 more sources

